Sentences with phrase «tissue by these molecules»

Chronic oxidative stress — meaning chronic presence of overly reactive oxygen - containing molecules and cumulative damage to tissue by these molecules — is a risk factor for the development of most cancer types.

Not exact matches

The calorie reductions were calculated individually through the ratio of isotopes absorbed by the participants» molecules and tissues over 2 weeks, a technique that accurately pinpoints a weight - maintenance calorie level.

Now, the «smart» bandage developed by the team provides direct, noninvasive measurement of tissue oxygenation by combining three simple, compact and inexpensive components: a bright sensor molecule with a long phosphorescence lifetime and appropriate dynamic range; a bandage material compatible with the sensor molecule that conforms to the skin's surface to form an airtight seal; and an imaging device capable of capturing the oxygen - dependent signals from the bandage with high signal - to - noise ratio.

Researchers at the University of California San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue — by feeding them adenosine, a naturally occurring molecule in the body.

Now the mechanism has been revealed, opening the way to using similar molecules in cancer treatments, to protect healthy tissue while tumours are destroyed by freezing.

By monitoring stem cell differentiation on gels that mimic the stiffness and nanofibrous structure of biological tissue, researchers have identified the specific molecules that stem cells use when selecting bone and cartilage fates.

The study, Lysyl oxidase and adipose tissue dysfunction, found that this molecule is more prevalent in fat tissue of obese people and that it was increased by inflammation and oxygen deprivation.

The research published in the journal Metabolism, examined a molecule called Lysyl oxidase (LOX) which regulates scarring by making tissue stiffer.

By pairing a receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating disease, as well as other conditions that involve either the brain or the eyes.

This observation implies that visceral fat causes insulin resistance by changing the output of molecules made by a wide range of fat tissues.

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, thanks to an imaging technique developed by University of Illinois researchers and clinical partners.

Platelet - rich plasma (PRP) is made by centrifuging a sample of a person's blood to isolate growth factors — molecules that trigger the growth of tissue and blood vessels.

A receptor is a molecule placed on the cell membrane which, in some cases, can direct material from the surroundings to be taken up by the cell and degraded, In the degradation of bone tissue, the receptor uPARAP plays a central role.

In 2013, a team led by Gradinaru together with Karl Deisseroth of Stanford University in California reported a method that strips away fats and other molecules to make intact brain tissue transparent, allowing thick sections to be imaged with a light microscope (see «See - through brains clarify connections»).

Cells migrate by connecting their cytoskeleton — a network made up of proteins — to adhesion molecules which in turn get in contact with the surrounding connective tissue.

This is a problem, says Frangioni, because when fluorescent molecules are injected into the blood, only a small fraction is taken up by the tissue of interest; the rest continue to circulate through the blood until filtered either by the kidneys or liver and excreted from the body.

The technique involves injecting antibodies into tissue infected with the bacteria together with molecules called photosensitisers, which are harmless until they are activated by light.

Mathematical models employed by the researchers suggest that the key is a molecule that inhibits branching, namely, a protein called transforming growth factor - β (TGF - β), which is produced by mammary cells and which is known to stop branching in developing tissues.

However, recent data suggest that in adipose tissue, proinflammatory molecules, including IL - 1β, PG - E2, TNF - α, and IL - 6, are produced by stromal vascular cells (SVCs)(33, 34).

Researchers at University of California, San Diego School of Medicine and University College Dublin (UCD) have found that augmenting a naturally occurring molecule in the body can help protect against obesity - related diseases by reducing inflammation in the fat tissues.

Despite the increased production of proinflammatory molecules, infiltration of adipose tissue by inflammatory cells has not been described as a common feature of obesity.

Here, 39 different RNA molecules are analysed in the same tissue and provide a more complete picture than the standard laborious method used by pathologist today.

Our therapeutic siRNA molecules are combined with delivery systems, which markedly enhance the efficiency and specificity of our siRNA drugs by directing them to the right cell type in the body and sparing healthy tissues.

The U.S. Patent and Trademark Office has announced that it will grant a patent to MDI Biological Laboratory scientists Voot P. Yin, Ph.D., and Kevin Strange, Ph.D., and their collaborator Michael Zasloff, M.D., Ph.D., for use of the small molecule MSI - 1436 to stimulate the repair and regeneration of heart tissue damaged by injuries such as a heart attack.

Nanocombinatorics holds promise for screening catalysts for energy conversion, understanding properties conferred by nanostructures, identifying active molecules for drug discovery or even optimizing materials for tissue regeneration, among other applications.

By injecting molecules called short interfering RNAs directly into tissue known as the trabecular meshwork, researchers have been able to silence the action of disease - relevant genes.

By utilizing the tools of cell and molecular biology, he studies the mechanisms by which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destructioBy utilizing the tools of cell and molecular biology, he studies the mechanisms by which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destructioby which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destructioby cells and alter their proliferation and specialization to either promote tissue growth or destruction.

The GI tract is where we break down food into much smaller molecules, that are then absorbed and used by the body to make energy, repair tissue, and clear toxins.

Under periods of stress (high activity level, trauma, malnutrition), branched chain amino acids are consumed by the body at an elevated rate, which not only catabolizes muscle tissue (as this is the biggest reservoir of these molecules), but makes it harder for the body to recover as levels are depleted.

The fat - burning properties of brown adipose tissue can be boosted by cold exposure, certain flavor molecules, and arginine - rich foods.

For example, foods such as meat, eggs, and beans consist of giant molecules of protein that must be digested by enzymes before they can be used to build and repair body tissues (15).

(iii) Many cancer patients, in particular those with advanced stages of the disease, exhibit altered whole - body metabolism marked by increased plasma levels of inflammatory molecules, impaired glycogen synthesis, increased proteolysis and increased fat utilization in muscle tissue, increased lipolysis in adipose tissue and increased gluconeogenesis by the liver.

Over time, this can turn into an autoimmune issue by which your immune system thinks your thyroid — or any other gland or tissue, for that matter — looks like the piece of steak molecule it's been fighting off for the past few years.

When consumed by humans, these molecules help to protect brain function and tissue from the aging process, repair DNA damage and increase life span.

KBs are then used by tissues as a source of energy3 through a pathway that leads to formation from β - hydroxybutyrate of two molecules of acetyl CoA, which are used finally in the Krebs cycle.

• Arthritis and rheumatoid arthritis (RA)-- Research by Cardiff University scientists found that frankincense can aid in inhibiting the production of key inflammatory molecules, helping prevent the breakdown of the cartilage tissue that causes these conditions.17

Normally, the immune system is prevented from acting on these whole protein molecules by the gut - associated lymphoid tissue, better known as GALT.

This is a molecule that plays a central role in how the body processes fats; it's produced by many tissues, including muscles.