Not exact matches
Then, to boost the number of
cells, which is another hurdle
in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem
cells from
bone marrow.
In a first step towards creating artificial sperm
cells, researchers have turned human
bone marrow tissue into primitive sperm
cells.
In experiments in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two week
In experiments
in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two week
in mice and human
cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T
cells mature and attracts blood
cells to the
bone marrow — halted disease progression
in bone marrow and spleen tissue within two week
in bone marrow and spleen
tissue within two weeks.
In conjunction with
bone marrow tissue cells, these HSCs form a microenvironment known as a niche.
There is only one exception: the stem
cells that are present
in the
tissues —
in the case of blood, the
bone marrow.
Prior research with cultured
tissue had shown that a mix of chemicals could change
bone marrow stem
cells from mice to those resembling brain
cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University
in Philadelphia tried the same brew on human
cells, the number altered was modest.
These findings may help explain why some people with mutations
in certain ribosomal protein genes develop conditions such as Diamond - Blackfan anemia — a blood disorder
in which the
bone marrow doesn't make enough red blood
cells — but don't have problems
in other body
tissues, Ware says.
Both the number and activity of osteoblasts —
cells that produce and reshape
bone tissue — were increased within the
bone marrow of mice with lung tumors compared with cancer - free animals; and reducing the number of osteoblasts
in mice not only limited neutrophil infiltration of tumors but also interrupted tumor progression.
In bone marrow transplants, for example, effects of SW033291 in accelerating tissue growth would provide the body the cells required to fight off the two most common and sometimes fatal complications, infection and bleedin
In bone marrow transplants, for example, effects of SW033291
in accelerating tissue growth would provide the body the cells required to fight off the two most common and sometimes fatal complications, infection and bleedin
in accelerating
tissue growth would provide the body the
cells required to fight off the two most common and sometimes fatal complications, infection and bleeding.
Now,
in a study recently published
in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition
in which the immune system attacks healthy
tissue following a
bone marrow or stem
cell transplant.
Rodriguez also concludes that including selective facial
bone structure
in addition to the chin of the donor provided natural
bone marrow stem
cells to help the transplanted face thrive following the surgery, and provided the necessary positional support for the facial soft
tissues.
In this tissue system, we can culture patient - derived megakaryocytes — the bone marrow cells that make platelets — and also endothelial cells, which are found in bone marrow and promote platelet production, to design patient - specific drug administration regimes.&raqu
In this
tissue system, we can culture patient - derived megakaryocytes — the
bone marrow cells that make platelets — and also endothelial
cells, which are found
in bone marrow and promote platelet production, to design patient - specific drug administration regimes.&raqu
in bone marrow and promote platelet production, to design patient - specific drug administration regimes.»
Understanding and reproducing key features of
bone marrow formation — and hence, the creation of blood
cells and platelets
in tissue culture for storage and later use — could help
in treatment of a variety of medical problems.
Together these data suggest that the F4 / 80 +
cells identified
in adipose
tissue are CSF - 1 — dependent,
bone marrow — derived adipose
tissue macrophages.
F4 / 80 +
cells in adipose
tissue are
bone marrow — derived.
Ovine
bone - and
marrow - derived progenitor
cells and their potential for scaffold - based
bone tissue engineering applications
in vitro and
in vivo.
Co-culture of
bone marrow fibroblasts and endothelial
cells on modified polycaprolactone substrates for enhanced potentials
in bone tissue engineering.
Comparison of human adult stem
cells from adipose
tissue and
bone marrow in the treatment of experimental autoimmune encephalomyelitis.
Adult stem
cells known as mesenchymal stem
cells (MSCs) are repair
cells that are found
in many
tissues of the body and have been studied for many years
in bone marrow.
Previously, stem
cells were found only
in bone marrow, brain
tissue and fetal
tissue — sources that have caused both logistical and ethical problems.
In addition, the organs and
tissues that possess high levels of SDF - 1, such as liver, lung,
bone marrow, and lymph nodes, attract the migration of CXCR4 - expressing cancer
cells [22].
Adult stem / progenitor
cells are present
in many organs and
tissues, e.g.,
bone marrow, teeth, heart, gut, kidney and liver, and remain quiescent for long period of time until activated by a disease or injury trigger.
Our previous studies have demonstrated increased inflammation
in adipose, pancreatic
tissue and mesenchymal stem
cells isolated from
bone marrow of WNIN / GR - Ob rats [14 - 16].
MSCs can be obtained from various sources
in the body, such as
bone marrow, adipose
tissue, umbilical cord etc., although the number of derived
cells varies significantly from one source to another.
Bone marrow - derived mesenchymal stem
cells (BM - MSCs) are obtained by isolating mononucleated
cells from a
marrow aspirate by centrifugation on a density gradient, followed by adherent
cell expansion
in tissue culture.
In contrast, adult stem
cells are derived from mature
tissue, typically from
bone marrow, but increasingly from most organs.
Regenexx involves harvesting a patient's
cells from
bone marrow, growing more
in a lab and then injecting the
tissue - repairing
cells into damaged joints or even lumbar discs.
In her project, Sipkins will investigate molecular characteristics of
tissue microenvironments, or «niches,» within the
bone marrow and how normal, healthy hematopoietic stem
cells, which give rise to the many kinds of blood
cells, compete with malignant
cells to occupy these coveted niches.
With this anti-aging supplement, the increase
in stem
cells released from the
bone marrow into the blood stream have the potential to become other types of
tissue cells with specialized function.
«
In the dish, you only have a select subgroup of immune system cells versus the mouse, where all of these cells were interacting and living in correct tissues and developing in different areas like bone marrow and spleen.&raqu
In the dish, you only have a select subgroup of immune system
cells versus the mouse, where all of these
cells were interacting and living
in correct tissues and developing in different areas like bone marrow and spleen.&raqu
in correct
tissues and developing
in different areas like bone marrow and spleen.&raqu
in different areas like
bone marrow and spleen.»
These lost
cells are replenished — like the water from the faucet — by «factory»
tissues in the
bone marrow.
Collection of samples of the
bone marrow tissue are helpful
in determining the cause of anemia or other blood
cell disorders.
The only white blood
cells that didn't originate
in the dog or cat's bone marrow are its lymphocytes - those were produced in its lymphatic tissues (lymph nodes, etc.); In dogs and cats, those are also the ones most likely to become cancerou
in the dog or cat's
bone marrow are its lymphocytes - those were produced
in its lymphatic tissues (lymph nodes, etc.); In dogs and cats, those are also the ones most likely to become cancerou
in its lymphatic
tissues (lymph nodes, etc.);
In dogs and cats, those are also the ones most likely to become cancerou
In dogs and cats, those are also the ones most likely to become cancerous.
This virus type inserts itself into healthy
cells in both the
bone marrow and the
tissues.
Feline Panleukopenia Virus (FPV), after entering into the body, destroys dividing
cells in the
bone marrow, lymph
tissues, epithelium (outer layer) of the intestine etc, thus severely depriving the immune system of the body.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band
cell — type of white blood
cell Baso basophil — type of white blood
cell Bile Acids digestive acids produced
in the liver and stored
in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating
cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood
cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure,
tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood
cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood
cells Hb, Hgb hemoglobin — iron rich protein bound to red blood
cells that carries oxygen (anemia, red
cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed -
cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood
cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red
cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed -
cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood
cell MRI magnetic resonance imaging (advanced
tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood
cell — immature red blood
cell (
bone marrow damage, lead toxicity) PCV, HCT, MHCT packed -
cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet —
cells involved
in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood
cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood
cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood
cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood
cell count (infection, inflammation,
bone marrow suppression)