Wanting to pursue more experimental research, he headed to the Massachusetts Institute of Technology for a postdoc to join a lab of engineers who focused on cell and
tissue culture experiments.
Not exact matches
Scientists are forced either to
experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in
tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.
Miho Sato and her colleagues at The Research Institute for Time Studies at Yamaguchi University in Japan did
experiments in mice and
tissue cultures to show, for the first time, that increases in insulin affect circadian rhythms.
In lab
experiments using
tissue samples
cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico Lung Institute have shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug.
Experiments in infected
tissue cultures demonstrated similar results, shortening the time to sterilization of the
tissue culture by seven days.
The drug as well as the physical contact of the microneedles with the scar
tissue contributes to the efficacy of the device, leading to the cessation of scar
tissue growth and a considerable reduction of keloids as demonstrated in laboratory
cultures and
experiments with animals.
Experiments in
tissue culture using neutralizing antibodies and CD155 receptor — specific antibodies and neurovirulence tests inCD155 transgenic mice confirmed that the synthetic virus had biochemical and pathogenic characteristics of poliovirus.
Although this «bystander effect» has been observed in
tissue culture and recently in living animals, no
experiments have yet linked it to the main reason for concern: Bystander effects might trigger cancer.
Those doses were chosen in analogy with the prion field, in which it is very common to observe that 1 % and 0.1 %
tissue homogenate containing prion protein aggregates is able to induce pathological changes both in cell
culture experiments and in in vivo animal models.
To ensure the best possible results for any
tissue culture - based
experiment, labs should routinely test for mycoplasma contamination.
For both
experiments,
tissues (ear skin, heart, bladder, spleen and tibiotarsal joints) of all mice injected with XT contents were uniformly
culture - negative.
Hence, its members favor primary cell lines and try to avoid
experiments with
cultured cell lines, they favor three - dimensional cell
cultures over two - dimensional cell monolayers that are cultivated on hard and flat surfaces and they try to maintain the three - dimensional context of plants, cell clusters,
tissues sections and small animal embryos.
Experimented production of new plant species from
tissue cultures and took efforts to develop it
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and
tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell
culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top
experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell
culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign
Tags for this Online Resume: Orthopaedic,
Tissue Engineering, Embryonic stem cells, Biomaterials, Nanotechnology, Biotechnology, Biomedical, Cell Biology, Anticancer, Clinical research, Teratology, Toxicology, Birth defects, Functional foods, Nutraceuticals, Antidiabetic, Antioxidants, selenium, Biochemistry, Plant biology, Proteomics, Plant physiology, Molecular Biology, Orthopedic, Cell
culture,
Tissue culture, Research, Teaching, Solution
culture, Crop physiology, Biochemical, in vitro, in vivo, Testing, Statistics, Hydroponics, Crops, Plants, Analysis, Designing,
Experiments, Scientist, Associate