Sentences with phrase «tissue culture models»

Using tissue culture models of cartilage and the meniscus, Levenston's team stresses the cells and tissues and studies what happens to them structurally and biochemically — for example, whether different genes are expressed, whether metabolism changes, or whether different types of cartilage cells respond differently to the same stress.

A549 lung epithelial cells grown as three - dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis.

Instead of growing cancer cells on plastic, they inserted a multi-layered omental tissue culture model into each well of a 384 - well or 1536 - well HTS platform.

Not exact matches

Specifically, I am investigating how the cAMP / PKA signaling pathway affects collagen structure and deposition, using a hydrogel - based, three - dimensional culture system to create a model that is more physiologically relevant than one produced by standard two - dimensional tissue culture methods.

Besides displaying more natural signaling patterns, 3D cultures allow researchers to mix cell types in ways that mimic their interactions in living tissue, providing more accurate models of normal physiology and pathogenesis.

One postdoc presents data on her efforts to develop an organoid model for small - cell lung cancer; another reports progress on culturing hormone - secreting organoids from human gut tissue.

Without such studies — for example in mouse models or tissue cultures — it is impossible to know which variants are responsible, Briggs says.

We have been using cell culture models and zebrafish as an assay to determine the effects of BMP on signaling, but we also want to be able to understand what the effect of the mutation is in the tissue and organ systems.

Those doses were chosen in analogy with the prion field, in which it is very common to observe that 1 % and 0.1 % tissue homogenate containing prion protein aggregates is able to induce pathological changes both in cell culture experiments and in in vivo animal models.

This video provides an overview of MimEX ™ Tissue Model Systems, a next - generation 3 - dimensional (3 - D) cell culture platform for the generation of ex vivo epithelial - derived organ tTissue Model Systems, a next - generation 3 - dimensional (3 - D) cell culture platform for the generation of ex vivo epithelial - derived organ tissuetissue.

Consisting of optimized media and reagents, MimEX ™ Tissue Model Systems provides an alternative to current 3 - D cell culture modes, such as organoids, with the added benefit of...

We exploit chick and mouse embryo animal models, combined with live imaging, cell and tissue cultures and molecular approaches.

This work involves behavior, immunohistochemistry (of brain tissue from mouse models of Alzheimer's), cell culture, and in vitro biochemistry.

Because of the lack of suitable tissue culture or animal models, studies to track their environmental sources and their pathogenesis in humans and identify emergent strains have been difficult.

Our lab uses a variety of model systems, such as the nematode C. elegans, as well as in vitro culture systems, to address fundamental questions in cell cycle control during development and tissue formation.

7/16/2008 Improved Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... More...

To address these different topics we are developing relevant animal models that will be used in combination with primary neuronal cultures, rodent brain slices, and brain tissues.

These epithelial organoid cultures are genetically and phenotypically extremely stable, allowing transplantation of the cultured offspring of a single stem cell, as well as disease modeling by growing organoids directly from diseased patient tissues (45).

3D cell culture provides a biomimetic model of cell systems for many applications including cell / tissue models and constructs for basic / medical research, product testing, and regenerative medicine.

Dr. Hackam's team has developed techniques of intestinal stem cell isolation and culture, and are working with tissue engineers and chemists towards the development of an artificial intestine, which has been tested in large and small pre-clinical models.

In particular, we use 2D and 3D in vitro cell cultures; tissue slices cultured ex vivo; and transgenic mouse models.

Viktor then applied his cell culture and model experience to create an edible and safe scaffold to support the growth of avian muscle tissue for his Senior Capstone Research Project.

Some phytochemicals which induce the Keap1 / Nrf2 pathway and have demonstrated protective effects in both neuron tissue culture and animal models of Parkinson's and neurodegenerative disease include:

Some phytochemicals that have demonstrated protective effects in both tissue culture and animal models of Parkinson's and neurodegenerative disease through the Keap1 / Nrf2 / ARE pathway include:

«Dr. Kim and I have been collaborating for over two years on an antiviral drug that proved highly active against the FIP virus in tissue culture and in a mouse model.

Tags for this Online Resume: morphology, molecular biology, tissue culture, animal model, cancer research, gene expression