Sentences with phrase «tissue culture studies»

Several years ago, in tissue culture studies of mouse neurons, Dr. Shelanski found that caspace - 2 plays a critical role in the death of neurons in the presence of amyloid beta, the protein that accumulates in the neurons of people with Alzheimer's.

Broccoli sprouts may protect the intestinal tract from harmful side effects associated with aspirin and other non-steroidal anti-inflammatory drugs, or NSAIDs, according to a tissue culture study published in the August 2012 issue of the journal «Current Pharmaceutical Design.»

A tissue culture study published in the «Journal of Medicinal Food» found that dandelion greens significantly suppressed nitric oxide, prostaglandins and cytokines — all known as pro-inflammatory molecules.

A tissue culture study of human breast - cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some forms of breast cancer by regulating estrogen receptors on breast cells and inhibiting growth and reproduction of estrogen - dependant breast - cancer cells.

A flavorful component of cinnamon oil, called cinnamaldehyde, may help prevent colon cancer, according to a tissue culture study of human colon cancer cells published in the May 2010 issue of the journal «Molecules.»

Not exact matches

Even an individual cell in our bodies is a responsive entity whose behavior can be studied in tissue culture.

This allowed them to track changes in calcium ion concentrations in the cells around wounds in living tissue (as opposed to the cell cultures used in many previous wound response studies) and to do so with an unprecedented, millisecond precision.

Miho Sato and her colleagues at The Research Institute for Time Studies at Yamaguchi University in Japan did experiments in mice and tissue cultures to show, for the first time, that increases in insulin affect circadian rhythms.

To study the role of sweet taste receptors, Cohen and lead study author Robert J. Lee, PhD, a post doctoral researcher in his lab, partnered with colleagues from the Children's Hospital of Philadelphia and the Monell Chemical Senses Center to analyze cultures and tissue samples from the upper respiratory tract of patients who were undergoing sinonasal surgery for a variety of conditions.

In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the lab.

In the study, the researchers show that after two to four weeks of 3 - D culture, the resulting muscle cells form muscle fibers that contract and react to external stimuli such as electrical pulses and biochemical signals mimicking neuronal inputs just like native muscle tissue.

Studies in mice and in tissue cultures suggest that giving vitamin C with tuberculosis drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen.

In this study, Nicchitta and his colleagues treated tissue culture cells with a stress - inducing agent called thapsigargin.

protected animals»); studies on in vitro systems (whole perfused organs, tissue slices, cell and tissue cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).

«You would never see these two effects if you were studying protein folding in a tissue culture dish, because you don't have the whole organism, C. elegans, in which you can look at the signals being communicated.»

Without such studies — for example in mouse models or tissue cultures — it is impossible to know which variants are responsible, Briggs says.

In the current study, the multi-institutional research team found that two of those 349 antibodies, known as ADI - 15878 and ADI - 15742, potently neutralized infection by all five known ebolaviruses in tissue culture.

Hutchison and Edgell are now studying the resurrected F promoters in tissue culture and in transgenic mice to find out how they differ from A promoters.

In the study, the researchers added LOX inhibitors to cultures from patients with Dupuytren's, keloids and other scar tissue, and detected changes using two - photon microscopy combined with biochemical and immunohistochemical analyses.

They describe this advance in a study published in Plant Cell, Tissue and Organ Culture.

Using tissue culture models of cartilage and the meniscus, Levenston's team stresses the cells and tissues and studies what happens to them structurally and biochemically — for example, whether different genes are expressed, whether metabolism changes, or whether different types of cartilage cells respond differently to the same stress.

«The 3D culture strategy used in our study can potentially be applied to other lineage progenitors for efficient formation of tissue organoids,» says co-first author Jun Wu, Salk research associate.

«Our stem cells also survive outside of mice, in a culture, so we can also manipulate them in a laboratory,» said Abad, adding that: «The next step is studying if these new stem cells are capable of efficiently generating different tissues such as that of the pancreas, liver or kidney.»

Another, previously unknown gene — when the investigators worked out its protein's structure and studied it in tissue culture — proved to do just the opposite: The protein helped the schizont leave the infected blood cell.

Washington, DC — January 3, 2018 — Studies in mice and in tissue cultures suggest that giving vitamin C with tuberculosis drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen.

Tissue - cultured corneal cells were used for in vitro studies rather than the usual lymphoid cells since corneal cells are the relevant target cells in vivo during corneal allograft rejection.

In a sense, heat shock proteins also have chaperoned Lindquist's career, beginning with her independent decision to study them in fruit fly tissue culture when she was a graduate student in the Harvard lab of Matthew Meselson.

Mouse Pancreas Tissue Slice Culture Facilitates Long - Term Studies of Exocrine and Endocrine Cell Physiology in situ.

In the current study, lead authors David V. Hansen, PhD, a postdoctoral fellow, and Jan H. Lui, a graduate student in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow individual cells and their progeny over time in cultured tissue slices from fetal cortex tissue that had been donated for research.

Katja Schurig (Storch, TUD)-- «Tissue engineering for reconstructing the central dopaminergic nigro - striatal pathway in Parkinson's disease: Cutting edge cell culture studies» (2012)

Because of the lack of suitable tissue culture or animal models, studies to track their environmental sources and their pathogenesis in humans and identify emergent strains have been difficult.

Nakabayashi, Monk, and collaborators studied methylation patterns in adult and umbilical blood and placenta cells from healthy volunteers; brain tissue from a brain bank; and a cultured liver cell line.

U-M's internationally renowned Translational Neuro - Oncology Laboratory generates novel primary cell cultures from pediatric and adult glioma tissue samples to study mechanisms of glioma growth and targeted treatment response.

Although originally studied primarily in two - dimensional in vitro assays, most cell migrations in vivo occur in complex three - dimensional tissue environments that are difficult to recapitulate in cell culture or ex vivo Further, it is now known that cells can mobilize a diverse repertoire of migration modes and subcellular structures to move through and around tissues.

Cell culture studies involve removing tissue (or even individual cells) from a plant or animal and growing them in a laboratory environment.

The cellular mechanisms underlying this bursting behavior have been studied in vitro, using either acute slices of the adult hypothalamus, or organotypic cultures of neonatal hypothalamic tissue.

In other laboratory studies, ellagic acid seems to reduce the effect of estrogen hormone in women in promoting growth of breast cancer cells in tissue cultures.

This study applied aluminum to rats, fibroblast cultures and chick embryos and discovered that collagen synthesis was inhibited in all tissues.

Performed Inventory and Procurement oversight and assisted and trained all students in activities such as Plasmid Construction, Elutriation of Whole Blood, Dendritic Cell Studies, Organ / Tissue Processing, Ctl Assays, Cell Culture Maintenance, Transfection, Animal Handling, Flow Cytometry and Microscopy.