Sentences with phrase «tissue regenerative capacity»

This valuable information could help scientists begin to explain why humans are less able to regenerate tissue and could also be used to improve the body's tissue regenerative capacity.

Not exact matches

And when I look at the regenerative capacity of other tissues in the body, I think «how can we take advantage of what nature has already figured out?»»

In addition to differences in regenerative capacity, the investigators also found an indicator of tissue fibrosis or «scarring,» profibrotic marker PAI - 1, was markedly elevated only after transmural injury.

Stem cells, which have to divide regularly to regenerate tissues with new cells, can produce telomerase, but not the amount required to counteract the shortening of telomeres that accumulates with aging: over time, the tissues have fewer fresh cells and they lose their regenerative capacity.

Mice fed a calorie - restricted diet showed a greatly enhanced regenerative capacity in their intestinal tissue (right).

MDI Biological Laboratory Associate Professor James A. Coffman, Ph.D., is studying the regenerative capacity of sea urchins in hopes that a deeper understanding of the process of regeneration, which governs the regeneration of aging tissues as well as lost or damaged body parts, will lead to a deeper understanding of the aging process in humans, with whom sea urchins share a close genetic relationship.

In 2017, he took up the position of Assistant Professor at the Fox Chase Cancer Center in Philadelphia, heading his own laboratory, which focuses on how tissue and organ degeneration, regeneration defects, and decline in regenerative capacity affect the initiation of cancer.

Cyclin A2: Increased levels of cyclin A2 have been shown to increase the regenerative capacity of heart tissue, one of an array of proteins that might for the basis for regenerative gene therapies for heart disease, and thus also might be beneficial to undergo far in advance of old age so as to slow or postpone degeneration in the heart.

In mammals, a single fertilized egg rapidly divides into several trillions of cells grouped into specialized tissues with marked differences in terms of developmental origin, regenerative capacity and ability to cope with damage.

When the heart muscle dies from lack of blood, it is replaced by scar tissue, since the heart has very little regenerative capacity.

Stem cells, which have to divide regularly to regenerate tissues with new cells, can produce telomerase, but not the amount required to counteract the shortening of telomeres that accumulates with ageing: over time, the tissues have fewer fresh cells and they lose their regenerative capacity.

However, by combining a biomaterial with proven regenerative capacity, like collagen, with a material that can carry an electrical stimulus, it may be possible to transmit electrical signals across damaged tissue, resulting in functional restoration of the affected area.

Thus, they may be a way to harvest the regenerative capacity of pediatric heart tissue without delivering the cells themselves.