Sentences with phrase «tissue tumor growth»

For many years, the Chinese have found asparagene to definitely help stop soft tissue tumor growth.

Not exact matches

According to ICES Director J. Tinsley Oden, mathematical models of the invasion and growth of tumors in living tissue have been «smoldering in the literature for a decade,» and in the last few years, significant advances have been made.

The tumor - derived peptide is identical in biological activity and similar in physiochemical properties to the still uncharacterized growth hormone - releasing factor present in extracts of hypothalamic tissues.

But its images can not distinguish malignant tumors from benign growths filled with harmless breast tissue.

Also limiting the use of therapeutic stem cells to date, self - renewal, a quality so vital to a fast - growing fetus, can also be a source of cancer risk when haphazard, unlimited cell multiplication results in the abnormal tissue growth seen in tumors.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

The authors propose that bacteria cross from the gut into the tissue of the intestinal wall, triggering inflammation that promotes tumor growth.

Tumors are notoriously difficult to study in their natural habitat — body tissues — but a new synthetic tissue environment may give cancer researchers the next - best look at tumor growth and behavior.

«About five percent of people have some kind of cartilage tumor in their bones, and in most cases it's because the growth - plate cartilage cells weren't fully replaced by bone tissue,» Alman said.

However, cancer cells may instead be coaxed to turn back into normal tissue simply by reactivating a single gene, according to a study that found that restoring normal levels of a human colorectal cancer gene in mice stopped tumor growth and re-established normal intestinal function within only 4 days.

In an article titled, «Allergen Induced Pulmonary Inflammation Enhances Mammary Tumor Growth and Metastasis: Role of CH13L1,» featured on the cover of the current issue of the Journal of Leukocyte Biology, this new research suggests inflammation raises the level of a known biomarker of cancer, called «chitinase -3-like-1» or «CHI3L1,» in the inflamed tissue, which leads to increased metastasis and faster cancer growth in that tGrowth and Metastasis: Role of CH13L1,» featured on the cover of the current issue of the Journal of Leukocyte Biology, this new research suggests inflammation raises the level of a known biomarker of cancer, called «chitinase -3-like-1» or «CHI3L1,» in the inflamed tissue, which leads to increased metastasis and faster cancer growth in that tgrowth in that tissue.

Sharma had developed a new method for studying how tumors with different characteristics respond to different immunotherapies: She would treat patients before their growths were surgically removed, then analyze the tissue in her lab.

Epidermal growth factor receptor (EGFR) mutations found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell lung cancer (NSCLC) patients correlates well with the EGFR mutations from patient - matched tumor tissue DNA.

But it has been harder to test whether cancer stem cells fuel the growth of tumors in other tissues.

Because those organoids include stroma, a scaffold of connective tissue essential for tumor growth, they may prove better for studying therapies that target the stroma, such as cancer immunotherapy.

In addition, masitinib strongly impaired tumor growth in all of the DLBCL patient - derived tissues that the team tested.

Investigators compared DNA from the liquid blood biopsies to DNA tissue samples from the tumor, using mate - pair sequencing — an inexpensive whole exome sequencing that can reveal genetic changes that contribute to tumor growth.

A major challenge in creating any type of organoid is determining the unique mixture of nutrients, growth factors, and tissue culture techniques that will transform patient tumor cells into miniature tumor organoids in a petri dish.

Depending on the type of tissue, it plays different protective and mechanical roles, but it has also been shown to be involved in a number of diseases, including the growth of cancer tumors.

The team also studied the copy number variations — genes that are not mutated but are amplified in the tumors to give them a growth advantage over normal tissues.

She says they can now identify the mechanisms that cause tumor growth in half of all adenocarcinomas, a family of cancer that affects skin and other tissue, including the lungs.

The biopsy of his primary tumor pointed to treatment with anti-HER2 therapy (Herceptin), but tissue from the metastatic biopsy, as well as cfDNA analysis, was negative for HER2 and positive for anti-epidermal growth factor receptor (EGFR) therapy (ABT - 806).

They showed that the iKnife could distinguish normal and tumor tissues from different organs, such as breast, liver, and brain, and could even identify the origin of a tumor that was a metastasis, a secondary growth seeded by a primary tumor elsewhere in the body.

When antibodies and other methods were used to dramatically deplete the supply of Tregs in mice, the researchers saw a dramatic jump in the numbers of activated dendritic cells and CD8 + T cells in pancreatic tumor tissue, as well as a slowing of tumor growth.

This repair, which was tested in mice and tissue cultures, slowed cancerous tumor growth.

Scientists think high levels of either protein could encourage tumor growth using similar pathways that they use to spur breast tissue growth.

«If we could prevent development of the new blood vessels in the cancer tissue driven by these signals, tumor growth and metastasis can be slowed down or prevented.»

Considerable previous research in cell cultures has demonstrated that low doses of ionizing radiation results in «bystander» effects, in which nearby, unexposed tissues suffer cell death, mutations, and tumor - inducing growth (ScienceNOW, 7 September 2005).

Zhang's laboratory now seeks to understand the mechanisms of the tissue - environment influence, opening the possibility that the environment could be altered in a way that fights cancer by preventing tumor cell growth.

The discovery that the tumor could exert its growth - enhancing effects on an isolated ganglion in tissue culture was the turning point of the investigation.

Scientists could also use the printed tissue constructs to shed light on activities of living tissue that require complex architecture, such as wound healing, blood vessel growth, or tumor development.

The researchers have shown that this marker protein changes myoepithelial cells in breast tissue to promote tumor cell invasion in vitro and enhances mammary tumor growth in vivo.

Jimenez - Garcia L, Herranz S, Higueras MA, Luque A, Hortelano S. Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarizaTumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarizatumor growth through modulation of macrophage polarization.

While much recent research has not been published in this area, there is actually a long history of studies that show: (1) there is a significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against cancer can be generated by vaccinating animals with embryonic tissues.

Early growth response 1 and fatty acid synthase expression is altered in tumor adjacent prostate tissue and indicates field cancerization.

To evaluate tumor growth in mice of each genotype, we used an orthotopic implant model derived from a spontaneous pancreatic tumor arising in a C57BL / 6 KPC mouse (33), which expresses mutant forms of K - Ras and p53 selectively in pancreatic tissue.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

Bottom Line: Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

Spheroids serve as models for the development of healthy tissues and their maintenance in the living organism but also as models for tumor growth (Pampaloni et al. 2007).

In the TNM staging system, cancer is assigned a letter that describes the tumor, node, and metastasis, and a number that designates its growth and spread into nearby tissue, lymph nodes, or distant organs.

When a tumor develops in the brain, spinal tissue, or affecting the nervous system, tumor growth is a significant concern due to the location around delicate tissue and structures.

Colonoscopy can detect early tumors, and more importantly pre-cancerous growths of tissue called polyps.

The surgery can be «open» — meaning, the doctor will make a large cut to remove the tumor, surrounding healthy tissue, and nearby lymph nodes all at once — or «minimally invasive,» in which a surgeon can use special tools to remove the growths by making a few smaller cuts.

The ability to construct new tissue is constrained on a protein - starved diet, so it's not surprising that tumor growth is slower when the tumor is large and protein is severely restricted.

«Tumor growth, invasion, and metastasis are multistep processes» that includes not just cell proliferation, but invasion through the surrounding tissue, and «migration through basement membranes» to reach the bloodstream before the tumor can establish «new proliferating colonies» of cancer cTumor growth, invasion, and metastasis are multistep processes» that includes not just cell proliferation, but invasion through the surrounding tissue, and «migration through basement membranes» to reach the bloodstream before the tumor can establish «new proliferating colonies» of cancer ctumor can establish «new proliferating colonies» of cancer cells.

What they found: Denosumab delayed and prevented tumor growth in the tissue samples and the mice.

These are caused by deterioration of organs or tissues, chronic inflammation of tissues, and abnormal growths or tumors.

Soft tissue surgeries (non-abdominal procedures) offered at Alpine Animal Hospital include removal of skin growths and soft tissue tumors.

can be a growth or fluid filled cyst or any structure rising above the normal surface of a tissue plane Malignant tumor

Ultrasound makes the use of sound waves to detect presence of fluid, abnormally thickened tissues or growths primarily in the chest and abdominal cavities of pets, but can also be used to detect the presence of soft tissue abscesses or tumors.