Sentences with phrase «tissues in normal mice»

Not exact matches

The researchers found that the tissue made normal connections with surrounding nerves and muscle tissues in the mice, and those connections allowed the tissue to function normally.

Lead author David W. Frederick, PhD, a postdoctoral fellow in the Baur lab, and the team generated mice in which they could restrict the amount of NAD in specific tissues in order to simulate this aspect of normal aging in otherwise healthy mice.

In contrast, control mouse pups dosed with plain saline solution showed normal connections throughout their cortical tissue.

Expression of CXCL16 was higher in the colon and lung tissue of GF mice than in normal mice, and blocking that expression reduced the numbers of iNKT cells and the amount of inflammation in those tissues.

However, cancer cells may instead be coaxed to turn back into normal tissue simply by reactivating a single gene, according to a study that found that restoring normal levels of a human colorectal cancer gene in mice stopped tumor growth and re-established normal intestinal function within only 4 days.

The researchers found that Sp7 in normal mice was expressed only in the dental mesenchymal tissue that gives rise to odontoblasts; it was not expressed in the oral epithelium that gives rise to ameloblasts.

When the researchers then induced stroke in mice either with or without the PARP gene, they found that the resulting tissue damage in the mice without the enzyme was 80 % less than in normal mice.

Dr. Baran Sumer (left) and Dr. Jinming Gao (right) and have invented a transistor - like threshold sensor that can illuminate cancer tissue, helping surgeons more accurately distinguish cancerous from normal tissue in mouse models.

As a result, they have less than half of the fat tissue found in normal, aged mice.

The characteristic scarring and loss of lung vasculature was slowed in every mouse, and the lung tissue of some mice began to return to normal.

The hind paws of the normal mice became hypersensitive and blistered in response to the UVB exposure, while those of the mutant mice showed little sensitization and tissue injury.

But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial types of cells — such as stem cells that can be extracted and cryopreserved from adult testicular tissue — as the starting point.

In normal mice, ginkgo halved the volume of brain tissue injured after a stroke, but it had little effect on mutant mice that lacked heme oxygenase.

The study showed that mice lacking the SNRK gene had a significantly higher concentration of macrophages in white fat tissue compared with normal mice.

They observed a significant decrease in the number of proliferating stem cells in the brains of HIV / gp120 - mice compared with similar tissue from normal, wild - type mice.

Now, they have investigated gene expression in low - grade dysplastic lesions and normal stomach tissue from mice and in gastric cancer and normal stomach tissue from humans.

Bottom Line: Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

We have applied the knowledge gained in our studies of SCID mice to optimize them to serve as hosts for human normal and malignant cells and tissues.

They were able to show that when mice were inserted with ErythroMer, the artificial blood was able to deliver oxygen to tissues in the same way as normal mice blood.