Insulin facilitates the transport of glucose from the blood to the cell by
binding to receptors on the cell membrane.
They work
by binding to receptors inside a cell, which then travel to the nucleus and act on the DNA by turning select genes on and off.
The hormone
then binds to its receptor and creates an adequate biological response within the cell, and effectively the body as a whole.
Once the fluorescent chemical
message binds to the receptor on the surface of the stem cell, the stem cell will «light up» under fluorescent light.
Less leptin crosses the blood brain barrier,
less binds to its receptors and the brain sends the signal to let you know it's time to eat again.
We want to know exactly which bits of the parasite protein are needed to
bind to the receptor in the blood vessel wall.
Once the sensors have traveled into a tumor's leaky blood vessels, they use special targeting molecules to
bind to receptors on the surface of blood vessel cells.
When an
opioid binds to a receptor in the peripheral nervous system, the nerve cells outside the brain, the receptor changes shape and sets in motion a cellular game of telephone that stops pain messages from reaching the brain.
Adenosine, when
bound to receptors of nerve cells, slows down nerve cell activity, this also happens during sleep.
One is a protein called protective antigen (PA),
which binds to receptors called TEM8 and CMG2 that are found on most mammalian cells.
Five years ago, researchers led by Dennis Discher, a cell biophysicist at the University of Pennsylvania, reported that in human cells CD47
binds to a receptor protein on macrophages called SIRPα.
This leaves your face swimming with oil and acne, because
insulin binds to receptors in your skin's sebaceous glands and stimulates them to produce more oil.
Working with prostate cell cultures, Meier and two students, Ze Liu and Mandi Hopkins, found the fatty acids
bind to a receptor called FFA4, for «free fatty acid receptor 4.»
One way dopamine influences intercellular communication is by
binding to receptors found in nerve cells, an action that can influence how likely these cells are to «fire» and communicate messages to other cells.
Specifically, when capsaicin frequently
binds to receptors within the human central nervous system's TRPV1 channel (the sensory receptor system for pain and heat detection), these receptors deplete and this depletion results in a whole host of benefits for the central nervous system at large, including terminating cancer cells, increasing the metabolic rate and digestive efficiency, increasing circulatory blood flow, and combatting inflammation, and making you feel better about the world.
Inflammation from pain and injury raises acidity, so this molecule could quash pain where necessary, but would
n't bind to receptors elsewhere in the body, reducing the likelihood of side effects.
Insulin
first binds to its receptor, which is present on the cell surface, and once it binds it triggers autophosphorylation of the receptor.
This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from
binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.
The researchers show that depleting PMN - MDSCs from the tumors or blocking FAS -
ligand binding to its receptor restored the ability of the T cells to kill induced tumors.
Lab testing showed that the plant - made virus particles, which
naturally bind to receptors on cancer cells, were taken in by human breast cancer cells.
Interestingly, the study shows that although these animals have high levels of dopamine, they do not show the normal response that should occur when
dopamine binds to its receptor, despite the fact that the levels of the receptor for dopamine are normal in these animals.
They discovered that a lipid molecule known as PIP2 is
usually bound to the receptor, but in the presence of capsaicin, it is released, creating a painful sensation.
It is now known that
hallucinogens bind to a receptor of the neurotransmitter serotonin; how the changes of consciousness influence the activity and connectivity of the brain, however, is not yet known.
Humans detect smells by inhaling air that contains odor molecules, which then
bind to receptors inside the nose, relaying messages to the brain.
Two studies published by Cell Press June 6th in the journal Cell identify mutations that increase the infectivity of H5N1 and H7N9 viruses through
improved binding to receptors in the human respiratory tract.
The endothelial cells have a receptor for transferrin that acts like a gatekeeper: When
transferrin binds to a receptor on the blood side of the barrier, the endothelial cell transports it (and its iron cargo) to the other side and spits it out into the brain.
«Our team discovered an enzymatic pathway that converts omega -3-derived endocannabinoids into more potent anti-inflammatory molecules that
predominantly bind to the receptors found in the immune system,» Das said.