The phrase
"to block this enzyme" means to prevent or stop the activity or function of a specific protein in the body.
Full definition
It works
by blocking an enzyme in the body that is needed to produce a substance that causes blood vessels to tighten.
Studies have shown that it may lead to significant weight loss by
blocking the enzyme in your body that trigger fat storage, reducing fat deposits.
Prescription blood pressure drugs
block an enzyme called ACE (angiotensin converting enzyme), and research has shown that eggplant inhibits ACE activity.
Cloves are especially rich with eugenol, a compound which helps
block enzymes which cause inflammation and prevents toxicity from environmental pollutants.
One
drug blocks an enzyme essential to the formation of amyloid plaques that are thought to cause the disease.
Antinutrients in soy
block enzymes needed for digestion, and naturally occur - ring phytates block absorption of essential minerals.
Many of the older drugs, such as tacrine, work by
blocking an enzyme involved in breaking down acetylcholine and are toxic to the liver.
Anti-Inflammatory Effects: Eugenol (one of basil's volatile oils) can also
help block the enzyme cyclooxygenase (COX) in the body.
Cherries, and particularly tart cherries, contain high concentrations of antioxidants and flavonoids that
block enzymes associated with inflammation.
They
also block enzymes involved in breaking down fat for energy, and thus can contribute to weight gain — especially the most inflammatory type of weight gain — around the waist, called omental fat.
Cherries are rich in anthocyanidins, powerful flavonoids capable of
blocking the enzymes responsible for sending «pain messages» to the cells, with analgesic effects comparable to those of ibuprofen and naproxen.
Lignin's protective characteristics persist during biofuel processing, where it's a big hindrance, surviving expensive pretreatments designed to remove it and
blocking enzymes from breaking down cellulose into simple sugars for fermentation into bioethanol.
Blocking the enzyme causes the cancerous cells to die, so the company is working with a telomerase inhibitor, imetelstat, that it hopes will kill tumor cells while leaving healthy ones unharmed.
The active ingredient in
aspirin blocks an enzyme that triggers cell death in Alzheimer's, Parkinson's and Huntington's diseases, offering hope for novel treatments.
They also determined that
blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.
PBO blocks enzymes that help resistant mosquitoes break down pyrethroids, so, in theory, the mosquitoes should become susceptible again.
In a test tube experiment, 6 -
HAP blocked the enzyme that builds DNA chains and prevented the chains from growing.
Sherman notes that when he was an undergraduate it seemed impossible that ailments like MS would be reversible — but last year, Sherman was first author on a paper in Annals of Neurology suggesting that
blocking the enzyme hyaluronidase might help the brain repair lesions associated with MS and other neurological disorders.
Blocking the enzyme inhibited the growth, proliferation and migration of GBM cells in laboratory studies, and it increased the number of GBM cells that died by apoptosis.
OV329 blocks an enzyme, called GABA - AT, that breaks down GABA, an «inhibitory» neurotransmitter that helps suppress the firing of some neurons.
By using enzyme tests and mass spectrometric studies using special 13C - labelled substrates (metabolite profiling), the scientists demonstrated that the new inhibitor
primarily blocks the enzymes Pks13 and Ag85.
Ibrutinib blocks the enzyme BTK (Bruton's tyrosine kinase), which is involved in maturing and activating B cells as part of the B - cell receptor's signaling pathway.
By injecting short nucleic acids into rats, researchers have
blocked an enzyme linked to swelling and tissue damage in the lungs.
Meanwhile, he and Kochan and their FDA and U-M colleagues will continue to study C. diff germination in mice and look for ways to
block the enzymes crucial to spore germination.
When researchers messed with the kissing bug to sabotage tyrosine breakdown, either by disabling genes or
chemically blocking the enzymes, the bugs died after dining, Oliveira and colleagues reported in Current Biology in 2016.
In the 22 June issue of Science, the team reports that the
phages block the enzyme made by a gene called murA, which, like the enzyme targeted by the other small phage, helps assemble cell walls.
A previously unknown group of compounds produced by the fungus Aspergillus fumigatus can
block an enzyme implicated in the build - up of cholesterol in arteries.
The researchers found much higher levels of heparanase in childhood brain tumours than in the normal brain, and furthermore, a molecule that can
block this enzyme induces cell death in medulloblastoma cells in culture, while normal brain cells were not affected.
A study conducted at the Case Western Reserve University School of Medicine in Cleveland discovered that the extracts contained in pomegranates
actually block the enzymes that are attributed to osteoarthritis.
Whereas most previous HIV
drugs block enzymes the virus uses to copy itself, the new ones take aim at different stages in the virus's life cycle (the virus is colored green in the micrograph below).
PARP (Poly ADP - Ribose Polymerase) inhibitors, such as olaparib, are targeted drugs that
block an enzyme involved in many functions in the cell, including the repair of DNA damage.