Sentences with phrase «to damage the organelle»
"To damage the organelle" means to cause harm or injury to a small specialized part within a cell called an organelle. Full definition
Lysosomes are responsible for the turnover and clearance from cells of damaged organelles and protein aggregates.
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They found that the cell recycling machinery is regulated by a protein called WHAMM, and that interfering with this protein or actin polymerization itself severely inhibits the cell's ability to recycle misfolded proteins and damaged organelles via autophagy.
The process of autophagy degrades damaged organelles, cell membranes and proteins, and protects against the aging process
Autophagy also plays a housekeeping role in removing misfolded or aggregated proteins, clearing damaged organelles, such as mitochondria, endoplasmic reticulum and peroxisomes, as well as eliminating intracellular pathogens.
This process was initially thought to be non-selective, but was later shown to be able to selective target damaged organelles (sub cellular components) and invading pathogens.
On the one hand, autophagy functions as a tumor suppressor mechanism by preventing the accumulation of damaged organelles and aggregated proteins.
Calcium regulates mitochondrial energy production, but too much can damage the organelle and even make the mitochondria rupture, also killing the cell.
Dr. Chu, who studies autophagy, or «self - eating,» in Parkinson's disease, was seeking a change on the mitochondrial surface that could signal to LC3 to bring in the damaged organelle for recycling.
Such findings are expected to be highly relevant to the aging process with particular impact on elucidating how to protect neurons from the accumulation of protein aggregates and damaged organelles.
It functions in the clearance of misfolded proteins and damaged organelles, as well as recycling of cytosolic components during starvation to compensate for nutrient deprivation.
The last but not least cool fasting - enhanced process worth mentioning here is cellular autophagy — a physiological process in the body that deals with destruction of damaged cells and stimulating new cell formation, which is really important for flushing out damaged organelles, pathogens, non-functional proteins and toxins, supporting tissue regeneration and preserving lean mass.
When resources are scarce, cells turn on recycling programs and send garbage collectors known as lysosomes to engulf and digest junk proteins and damaged organelles, enabling re-use of their amino and fatty acids.
During autophagy, bacteria and viruses, as well as junk human proteins and damaged organelles, are digested.