Sentences with phrase «to develop biomarkers»

«Further research into the mechanisms and etiology of the health problems of (Gulf War) veterans is critical to developing biomarkers of exposure and illness, and preventing similar problems for military personnel in future deployments.

develops biomarkers for early diagnosis and improved treatment of cancer, with the objective of enabling personalised treatment at an early stage.

«The markers we identified can be used to develop a biomarker panel for pre-symptomatic testing even among people who did not have a family history,» Iyengar indicated.

New clues about this protein could help scientists develop a biomarker that could diagnose Parkinson's disease earlier, Liddle said.

Importantly, the research team, funded by Cancer Research UK and the Medical Research Council, have also developed a biomarker test to identify SETD2 mutated tumors, something that can be used immediately in cancer diagnosis.

Future studies will focus on developing biomarkers capable of making early predictions on whether patients will develop a severe form of the disease.

«Future research will focus on optimizing the candidate therapies discovered by our team in this study as well as developing biomarkers that can be used to test the efficacy of other potentially promising drugs,» says Dr. Rothstein

Without really good markers for the disease's occurrence, for glaucoma progression, it's hard to develop new drugs and test them on people and determine whether or not those drugs are really good for the disease in a reasonable time period so developing biomarkers is going to be good both for glaucoma disease protection as well as for disease treatment.

«We can potentially develop some biomarkers that allow us to diagnose it earlier,» MacKenzie said.

Potter's research has been aimed at understanding the risk and biology of colorectal, breast and pancreatic cancers, developing biomarkers for screening and early detection, and monitoring cancer progression in high - risk individuals.

«We are excited to work with RBM to leverage their MAP technology to develop a biomarker panel for SMA that will help evaluate responses to treatments more efficiently and minimize the burden of clinical trials for patients and families.»

One goal the researchers have is to identify that cell and its biological mediators to see if it possible to develop a biomarker that might allow development of a blood test for food allergies.

She says getting the correct dosage is all - important and plans to develop a biomarker to show whether the BCG is having even a subtherapeutic effect on the immune cells that target islets.

Belisle's research is rooted in tuberculosis and leprosy, but he saw that the approaches his team has taken with those diseases — developing biomarkers or biosignatures for diagnosing a disease or the prognosis for a disease — could be applied to developing a diagnostic test for STARI and improving Lyme disease diagnostic tests.

«While a great deal of money has been invested in developing schizophrenia drugs, a similar investment hasn't been made to develop biomarkers that could improve the reliability and consistency of test results,» said Daniel Javitt, MD, PhD, professor of psychiatry and Director of the Division of Experimental Therapeutics at CUMC, Director of schizophrenia research at the Nathan Kline Institute for Psychiatric Research, and Co-Principal Investigator of the study.

Analysis of gene expression will be performed to develop biomarkers and predictors of protection.

Belisle saw that the approaches his team has taken with tuberculosis and leprosy — developing biomarkers or biosignatures for diagnosing a disease or the prognosis for a disease — could be applied to developing a diagnostic test for STARI and improving Lyme disease diagnostic tests.

Our goal is to develop biomarkers that directly assess the function and metabolism of ganglion cells and these will be better able to distinguish successful drugs in clinical trials.

Dr. Vivek Srinivasan: Work in my laboratory is attempting to build upon the results in Dr. Huberman's laboratory to use his finding of specific early changes in one layer of the retina in early glaucoma and to develop biomarkers for those changes based on the energy usage and microvasculature in that layer.

The CFC researchers have been testing various hypotheses to develop a biomarker that eye doctors can use to identify glaucoma at a much earlier stage in its progression than current detection methods.

Because different tissue antigens are targeted in different diseases, and some conditions target a diverse array of autoantigens, it is challenging to develop biomarkers of tolerance.

Miller is widely recognized for his research on the impact of toxins in Parkinson's disease (PD) and has created a unique mouse model of the disease to develop biomarkers of exposure, risk and early disease.

Specific Aim 2: Develop biomarkers and imaging techniques to improve detection and predict efficacy of current and novel therapeutics for gastrointestinal cancers

PNNL scientists are using the improved sensitivity in studies to develop biomarkers for early disease diagnosis, drug target discovery and basic biological research.