Sentences with phrase «to identify biomarkers»

A team of scientists, led by researchers at the University of California, San Diego School of Medicine and Zacharon Pharmaceuticals, have developed a simple, reliable test for identifying biomarkers for mucopolysaccharidoses (MPS), a group of inherited metabolic disorders that are currently diagnosed in patients only after symptoms have become serious and the damage possibly irreversible.

When Lipkin was interviewed this past November about a 2 - year, $ 766,000 project on CFS / ME funded by NIH, on which he and Hornig are co — principal investigators, Lipkin credited several external collaborators but did not mention Hornig's contribution to the work, which aims to identify biomarkers of CFS / ME.

However, Grigsby says the idea of identifying biomarkers in breath could be applied to monitoring various aspects of health, such as fatigue, in commercial pilots too.

Recent research identified biomarkers associated with inflammation that are elevated in HCM patients.

«Researchers identify biomarker for glaucoma damage.»

In order for early intervention of addiction to be possible, the study has deemed it essential to identify the biomarkers which may make a person more vulnerable to drug addiction, due to these particular areas of the brain affecting decision making and impulsivity.

A newly identified biomarker panel could pave the way to earlier detection and better treatment for pancreatic cancer, according to new research from the Perelman School of Medicine at University of Pennsylvania.

Wong's research over the past decade has focused on identifying biomarkers in saliva.

«Proteins in your runny nose could reveal a viral infection: Scientists identify biomarkers in mucous that verify viral infection from cold or flu.»

In this context, FAST - Psychosis researchers identified biomarkers using MRI applications to support the development of drugs that target the glutamate system.

This finding — which also identifies a biomarker that can be used to gain a deeper understanding of the proteasome inhibitor - resistant state — is reported in the Proceedings of the National Academy of Sciences (PNAS) in an article entitled, Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

«We hope that our work will provide the basis for a larger study of patient samples that may ultimately identify biomarkers that can be used as surrogate markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay disease onset.»

Two Northwestern University scientists have identified a biomarker strongly associated with basal - like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy.

Adams says more research is needed — such as identifying biomarkers, testing combination therapies and expanding clinical study to larger patient cohorts.

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

They have now used the tools of Social Network Analysis (SNA) to help them unravel the connections and identify the biomarkers present in patient genomic microarray data.

Furthermore, the researchers identified biomarkers unique to the R - NSC type, as well as signaling pathways required for the maintenance of the R - NSC type.

Katerina Akassoglou, PhD, a senior investigator at the Gladstone Institutes, seeks to solve this problem by identifying a biomarker for MS in the blood that can track the progression of the disease.

«Our MAP technology has been effective as part of many therapeutic development programs and for identifying biomarker patterns linked to complex diseases.

The team will then compare the microbiome and molecular profiles of the healthy aging group with those of the non-healthy aging group to identify biomarker candidates.

«With rarer mutations in particular there aren't enough patients for large clinical trials to be able to identify biomarkers of resistance, but by considering all the different potential genetic factors that have been identified together in one study, we can robustly predict from experiments in laboratory dishes how cancers with different genetic mutations will respond to different treatments.»

Using fungal isolates that Ali provided, Sapakhova became familiar with methods of identifying biomarkers for the tan spot toxin genes using polymerase chain reaction analysis and gel electrolysis.

The newly identified biomarker, a gene called RASAL2, provides a target for developing new therapeutics designed to treat this often deadly disease.

«Unlocking the secrets of Ebola: Scientists identify biomarkers that indicate likelihood of survival in infected patients.»

Syed P et al. (2016) Autoantibody Profiling of Glioma Serum Samples to Identify Biomarkers Using Human Proteome Arrays Sci Rep2015 Sep 15; 5:13895.

Scientists at A * STAR's Genome Institute of Singapore (GIS), in collaboration with local clinicians and colleagues in the USA, have identified a biomarker which is strongly associated with triple negative breast cancer (TNBC), a highly aggressive carcinoma that often has early relapse and metastasis following chemotherapy.

«For example, we use very similar algorithms to analyse disease - associated patterns in the genome and identify biomarkers in clinical cell screens.»

Yet Zetterberg, who has been identifying biomarkers associated with brain injury and other neurological disorders in his lab, questions the usefulness of UCH - L1 as a concussion biomarker, and says his own testing has found it unreliable.

Much current research in immuno - oncology focuses on improving these treatments, for example, by finding new immunotherapy targets and identifying biomarkers that predict a patient's response.

By pinpointing one pathway of iCCA, this study opens up a new line of investigation to identify biomarkers of the disease.

It is proving invaluable in identifying biomarkers and pinpointing potential drug targets for many diseases.

In other investigations, they are seeking to identify biomarkers in the blood that could lead to earlier detection of fibrolamellar and better tracking of patients» progress after tumors are surgically removed.

Because individuals — both on and off the battlefield — can suffer from mild TBI and not know it, identifying a biomarker could help speed up clinical care, says study investigator Jennifer Rusiecki, an epidemiologist at Uniformed Services University of the Health Sciences in Bethesda, Md..

He identified biomarkers with therapeutic potential, filing three patents and joining, as data manager, a proof - of - concept clinical trial to determine immunogenetic predisposition to gastrointestinal cancer.

Scientists are trying to identify biomarkers that could predict and improve SAH outcomes.

To identify patients at risk for DCI, Powers is studying the quantities of micro-RNAs that are created in the hours and days after a hemorrhage to see if he can identify biomarkers that could help predict the delayed stroke.

Our knowledge of immune - related pathologies in the brain and the ability to identify biomarkers for disease and inflammation are key for forming meaningful mechanistic conclusions.

Dr. Montano is also a principal investigator on a Boston OAIC Pepper Center project to identify biomarkers for anabolic response.

This is a multicenter study to identify biomarkers of ASD.

Therefore, a crucial endeavor of the group is to identify biomarkers — molecular or cellular changes that can be measured fairly easily from blood — that would provide accurate information to predict whether granulomas are likely to remain latent or transition to active infection.

«Ultimately, we would like to be able to identify a biomarker for cognitive impairments due to excessive sleepiness.»

Now, research published in International Journal of Data Mining and Bioinformatics shows how social network analysis can be used to understand and identify the biomarkers in our bodies for diseases, including different types of cancer.

The researchers used mass spectrometry to identify biomarkers of metabolic differences in the two diseases.

The new trial — estimated to cost at least $ 100 million overall, with most of the remaining funds provided by partners in the pharmaceutical industry — will be part of the Alzheimer's Prevention Initiative, a large consortium of researchers attempting to identify biomarkers and treatments that can slow or stop the disease.

«There has been an utmost urgency to identify biomarkers for mental illness that could significantly impact research and drug development,» said Xianjin Zhou, PhD, assistant professor in the Department of Psychiatry at UC San Diego School of Medicine and lead author.

Researchers at Columbia University Medical Center (CUMC) and the New York State Psychiatric Institute (NYSPI) have identified biomarkers that can aid in the development of better treatments for schizophrenia.

The researchers» approach «to identify biomarkers is certainly elegant and innovative,» writes Michel Boussinesq, an onchocerciasis expert at the Institute of Research for Development in Montpellier, France, in an e-mail.

«But we've identified a biomarker that seems to correlate with disease severity in patients, and what that marker is measuring is stress to the cells rather than cell death.

Dr. Zilliox is using next - generation sequencing to identify biomarkers that could predict whether a kidney lesion is benign or cancerous.