Our work suggests that studying PI (3,4) P2 - regulated processes may reveal why PTEN is such a powerful tumour suppressor and may also help us to
identify new therapeutic targets in PTEN - mutated cancers.»
The system can be used by researchers as a model to elucidate how viral infections contribute to exacerbations, gain insight into mechanism of action of drugs, and could potentially
help identify new therapeutic targets.
COPD is now considered to be a disease of accelerated ageing of the lung, and understanding the molecular signalling pathways involved in the ageing process (cellular senescence) has identified new therapeutic targets [37].
Kilian's main research interests comprise the functional exploration of cellular signaling networks by the development of specific chemical probes and chemical biology approaches apt to
identify new therapeutic targets relevant for the treatment of human disease.
The Cell Surface Signalling Laboratory is interested in
identifying new therapeutic targets for both genetic and infectious diseases by using large - scale systematic approaches to discover receptor - ligand interactions that are essential for cellular recognition processes.
Further functional studies will be needed to define the role of these genes and to
identify new therapeutic targets to treat chronic wound disorders that cost each year billions of dollars», explains Cédric Blanpain, the senior and corresponding author of this new study.
Professor Andrew Lotery, who led the Southampton contribution, hopes the findings may help improve the understanding of the biological processes that lead to AMD and
identify new therapeutic targets for potential drug development.
If we can figure out how prostate cancer cells alter the environment inside bone to induce this osteoblastic process, we can start to
identify new therapeutic targets.»
The Pediatric Cancer and Tumor Evolution and Progression working groups jointly recommended efforts to
identify new therapeutic targets to overcome cancer resistance.
The Cell Surface Signalling Laboratory investigates the molecular basis of cellular recognition processes to
identify new therapeutic targets for both genetic and infectious diseases.
One of its priorities is to develop relevant strategies to decipher multiple forms of neuromuscular diseases,
identify new therapeutic targets and foster novel strategies for innovative treatments.
Jun. 25, 2015 — Vanderbilt researchers have received a $ 2.15 million grant to study the amount and activity of «brown fat» in adults, with the aim of understanding its role in metabolic disease and
identifying new therapeutic targets.
This project has the potential to uncover clinically relevant mechanisms of cellular senescence in fibrosing ILDs and identify new therapeutic targets
Most importantly, Dr. Mucke has
identified new therapeutic targets and experimental strategies to block these disease - causing processes and to make the brain more resistant to disease.
in a middle - term, exploit the experimental systems established, to identify the direct causative factors (genetic, environmental, iatrogenic) involved in the initiation of chromosomal alterations and disease progression, and to
identify new therapeutic targets;
Researchers in the Perelman School of Medicine at the University of Pennsylvania have
identified a new therapeutic target for the treatment of melanoma.
Dr. Kemp leads a program in functional genomics to
identify new therapeutic targets for human cancer, supported largely by a U01 grant in the Cancer Target Discovery and Development Network.
This new understanding could help us to
identify new therapeutic targets for improving motor neuron survival.»