Sentences with phrase «to respond to standard therapies»

Researchers in the Department of Pharmaceutical Sciences at the Leslie Dan Faculty of Pharmacy, University of Toronto have developed a new technology for liquid biopsy to identify which patients may not respond to standard therapy before it is delivered.

Toronto, ON, Canada (Scicasts)-- Researchers have developed a new technology for liquid biopsy to identify which patients with prostate cancer may not respond to standard therapy before it is delivered.

Ninety percent of children and adults with acute lymphoblastic leukemia (ALL) who had relapsed multiple times or failed to respond to standard therapies went into remission after receiving an investigational personalized cellular therapy, CTL019, developed at the Perelman School of Medicine at the University of Pennsylvania.

Inclusion Criteria: • Pathologically proven acute myeloid leukemia (AML) or intermediate, high - risk, or very high risk Myelodysplastic Syndrome (MDS) as defined by the World Health Organization (WHO) criteria or Revised International Prognostic Scoring System (IPSS - R) which is relapsed or refractory (R / R) to standard therapy and / or for which standard therapy is contraindicated or which has not adequately responded to standard therapy.

«Drug resistance continues to be a major challenge across many cancer types so it's vital that we explore new ways to tackle tumours that have stopped responding to standard therapies.

The drug, a monoclonal antibody called ipilimumab, is the first treatment of any kind ever shown in a large, randomized phase III clinical study (study MDX010 - 20) to improve overall survival in patients with metastatic melanoma who no longer respond to standard therapy.

Its first indication is a rare cancer that affects only 3,100 new patients each year, and the drug only targets roughly 30 % of those patients who do not respond to standard therapy.

A new study published online by JAMA Neurology examines the long - term outcomes of patients with aggressive forms of multiple sclerosis (MS) who failed to respond to standard therapies and who underwent autologous hematopoietic stem cell transplantation using their own stem cells.

The first phase of the clinical trial of the unique pairing is looking at the safety of combining the two drugs in a dozen patients with solid tumors, like lung or liver cancer, who have not responded to standard therapy.

Two challenges in treating patients with estrogen - positive breast cancer (ER +) have been an inability to predict who will respond to standard therapies and adverse events leading to therapy discontinuation.

Nitrous oxide, or laughing gas, has shown early promise as a treatment for severe depression in patients whose symptoms don't respond to standard therapies, according to a small pilot study led by (from left) psychiatrists Charles R. Conway, MD, and Charles F. Zorumski, MD, and anesthesiologist Peter Nagele, MD, at the School of Medicine.

On June 18, 2013, the FDA bowed to pressure and partially reversed course, agreeing to exercise «enforcement discretion» for fecal microbiota transplants used to treat C. diff infections that weren't responding to standard therapy.

We provide screened, frozen, ready - to - use human fecal microbiota preparations for the treatment of recurrent Clostridium difficile infections not responding to standard therapies.