Sentences with phrase «to respond to the drug»

And scientists were so uncertain about what chemical imbalances impacted which neural circuits that one - third of people with major depression did not respond to drugs at all.

Some patients respond to the drug for years, but in other patients, the treatment either fails early, or the cancer evolves resistance.

They found that the infected cultures responded to the drugs in the same way that liver cells inside the body are known to do.

Treatment with drugs will help with the pain and mobility, but as the condition advances some cases fail to respond to drug therapy.

However, profiles of gene expression may not fully capture all of the ways cells respond to drugs.

Unfortunately, however, in most cases a kind of resistance develops: Eventually, the cancer cells no longer respond to the drug and the tumor spreads again.

Half were engineered to respond to the drug by disabling the gene — a step that would protect their eyes.

About 50 % of the dominant aggressive dogs respond to these drugs, with a decrease in aggressive displays.

Although the differences are small, they show up in the diseases that different groups get and how these groups respond to drugs.

The role of the family - and family - based interventions - in responding to drug problems has been the subject of research internationally.

About 30 percent of epilepsy patients don't respond to drugs to prevent seizures.

Those genes might influence how patients respond to drugs, or what side effects they experience.

The arrhythmia did not respond to drug treatment, so anesthesiologists were brought in to perform left stellate ganglion block, an injection of medication into a nerve bundle in the neck, allowing diagnosis and further treatment.

And one of the Council's associate directors, Dr. Jedd Wolchok, recently presented the results of a trial using ipilimumab and nivolumab, two immunotherapies mentioned in the article, that showed a remarkable 40 percent of late - stage metastatic melanoma patients responded to the combination treatment compared to 7 percent and 28 percent who responded to each drug given alone.

Pharmacogenetics is the study of how different groups of people respond to drugs, based on their genetic makeup.

Behavior therapy augments response of patients with obsessive - compulsive disorder responding to drug treatment.

Paclitaxel and another chemotherapy drug, carboplatin, are considered standard, first - line treatments for advanced ovarian cancer, experts say, and most patients respond to the drugs initially.

Future research will apply this finding to other cancers, specifically looking at patients with non-Hodgkin Lymphoma to see if patients who are not responding to drugs like idelalisib have this particular mRNA variation.

Uveal melanoma does not respond to the drugs given to patients with melanoma on the skin; and, in fact, there is no drug approved specifically for treatment of the disease.

«Although only a small subset of women responded to the drug, within that subset pembrolizumab worked extremely well and responses were durable,» Adams adds.

«This should greatly improve our understanding of the genomics of bladder cancer, how these tumors respond to drugs, and how they develop drug resistance.

The fMRI technology developed for the study has the potential to usher in an era of individualized pain therapy by enabling targeted pain medication based on how an individual's brain responds to a drug.

An explosion of recent studies in both animals and people suggests that resident microbes can influence susceptibility to diseases from HIV to asthma, predispose to obesity across generations, and tinker with how the body responds to drugs.

Human breast tumors transplanted into mice are excellent models of metastatic cancer and are providing insights into how to attack breast cancers that no longer respond to the drugs used to treat them, according to research from Washington University School of Medicine in St. Louis.

Pharmacogenomics uses a person's genes to explain the difference between how one person responds to a drug compared to another.

Sometimes a different one will do the trick, but in Reid's experience, about 10 to 20 percent of depressed people respond to no drug at all.

Some epileptics who don't respond to drugs undergo brain surgery.

A clinical trial has shown that patients with a specific molecular subtype of diffuse large B - cell lymphoma (DLBCL) are more likely to respond to the drug ibrutinib (Imbruvica) than patients with another molecular subtype of the disease.

Her group also found that giving mice fecal transplants from patients who did or did not respond to the drugs led to similar outcomes in the animals.

Some cancers do not respond to drugs because cancerous cells have efflux pumps.

People who exhibit a resistance to aspirin may be more likely to have more severe strokes than people who still respond to the drug, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015.

Next, the company's chief scientist said, Nitromed would search for biochemical and genetic markers that might predict the sort of patient who best responded to the drug.

Different cell types respond to these drugs in qualitatively different ways.

Four out of the 10 colon cancer patients with the defect and 5 out of the other 7 cancer patients with the abnormality responded to the drug.

You can also see how the HD brains - on - a-chip respond to drugs.

The researchers have developed what's called a «biomarker» (biological marker) that predicts whether patients will respond to the drug Avastin.

Dogs suffer from naturally occurring compulsive disorders that closely model human OCD, manifested as an excessive repetition of normal canine behaviors that only partially responds to drug therapy.

In addition, patients with bovine TB often do not respond to the drugs commonly used to treat TB, sometimes resulting in a fatal outcome.

For example, the goal of the drug response challenge is to predict how a tumor will respond to a drug based on the characteristics of both the tumor and the drug, the information for which is identified through previously available data, such as tumor samples and previous drug screens.

Researchers will determine if genetic mutations are directly linked to how well or how poorly a cat with heart disease responds to the drug,» Morris stated.

Dogs with this atypical disorder generally respond to drugs like mitotane or trilostane, similar to dogs with typical or classical Cushing's disease.

Analytical skills needed to effectively review the appropriateness of medication orders and to respond to drug information questions...

Behavior Therapy Augments Response of Patients With Obsessive - Compulsive Disorder Responding to Drug Treatment

Rogue antibiotics pose a different kind of challenge, encouraging the spread of antibiotic resistance, in which disease - causing bacteria stop responding to drugs.

Novartis will get paid $ 475,000 only if patients respond to the drug by the end of the first month of therapy.

«Although only a small subset of women responded to the drug, pembrolizumab worked extremely well in that subset and responses were durable,» Dr. Adams adds.

Using 80 of the successful tumor xenografts — from the Greek «xenos» meaning «foreign» — he compared how the mouse's tumor responded to a drug or drug combination with the treatment response of the corresponding human patient.