Sentences with phrase «tolerated at the doses»

In this study, ISIS - SMNRx was well tolerated at all dose levels in children with SMA.

Tabrizi - «The drug was safe and well tolerated at all doses tested».

Not exact matches

Key findings presented at AACR included sustained peripheral NK and T cell expansion, doses were well - tolerated and the drug candidate's role as a long - acting CD122 agonist without targeting CD25.

Chemotherapy drugs are usually administered to cancer patients every few weeks at a high «maximum tolerated» dose.

Pembrolizumab, marketed under the name Keytruda, was well tolerated by both cohorts at a 200 mg dose every three weeks, according to study results.

The study, presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, also showed that the fixed - dose combination of LDV / SOF was well - tolerated, and no patients experienced a serious adverse event considered related to the study drug.

At the end of the trial period, the researchers found that 41 of the 49 therapy recipients could tolerate the 800 mg dose safely — and 24 of them could even handle 1400 mg.

(1) Resistant hypertension (rHTN) is defined as office blood pressure greater than 160/90 mmHg, systolic ambulatory blood pressure greater than 135 mmHg and failure to respond to more than 3 appropriate drugs at the highest tolerated doses including diuretics.

In this study, NPT088 was safe and well - tolerated at multiple dose levels, with a suitable pharmacokinetic profile.

At the end of the dose - finding phase, the maximum - tolerated dose was avelumab at 10 mg / kg every 2 weeks and axitinib at 5 mg twice dailAt the end of the dose - finding phase, the maximum - tolerated dose was avelumab at 10 mg / kg every 2 weeks and axitinib at 5 mg twice dailat 10 mg / kg every 2 weeks and axitinib at 5 mg twice dailat 5 mg twice daily.

C188 - 9 was administered at the maximum tolerated daily dose (100 mg / kg BW) based on drug toxicity studies carried out in mice by Dr David J Tweardy.

They further noted that doses of 1.3 to 1.5 grams of Collargol are tolerated (before death occurs) if divided and given at the proper intervals over a period of 3 to 7 days.

It reports that GI distress can be caused at a high dose, but overall, they are very well tolerated in the human body (15).

Then, we'll add in some B12, Methyl B12, at a small dose to see how they tolerate it.

You might want to consider taking a really low dose that your body can tolerate and try it for at least six months.

In these cases, I generally recommend spore - form supplements like MegaSporeBiotic at a low dose that is gradually increased as tolerated.

A lot of people will get diarrhea or loose stools on them... Find the dose at which your bowel is tolerating that electrolyte load.

Now consider that Chlorogen800 Green Coffee Bean Extract is a higher dose than many supplements, at 800 mg, and very well - tolerated for people with no specific health concerns.

Subcutaneous administration of Onsior (robenacoxib) injection at a dose of 2 mg / kg (0.91 mg / lb) once daily for up to 3 days, with the first dose administered approximately 45 minutes prior to surgery, was effective and well - tolerated for the control of postoperative pain and inflammation with soft - tissue surgery in dogs.

Administration of Onsior Tablets for Dogs at a dose of 2 mg / kg (0.91 mg / lb) once daily for up to 3 days, with the first dose administered approximately 45 minutes prior to surgery, was effective and well - tolerated for the control of postoperative pain and inflammation with soft - tissue surgery in dogs.

Ivermectin toxicity Many dogs can tolerate the low dose required to prevent heartworms but when ivermectin is used to treat the many other parasitic infections in dogs it is used at much higher doses and the likelihood of toxicity increases.

The majority of adverse events were mild in severity and similar to the placebo group in frequency.6 In a separate safety study, SIMBADOL was well tolerated at up to five times the label dose for up to nine days.7

This medication is usually well tolerated by dogs and cats when given at the correct dose Contact your veterinarian if your pet experiences any of these symptoms: fast heart rate, excessive ingestion of food, inability to tolerate heat, excitability, nervousness, excessive panting.

Clomicalm Tablets were demonstrated to be well - tolerated in dogs at the recommended label dose of 2 - 4 mg / kg / day.

Manchester Terriers tolerate premedication well prior to anesthesia with acepromazine / opioid combinations given IM or SQ, provided that acepromazine is used at the lowest effective dose.