Surprisingly, after this correction,
the total intracranial volume was still about 4 % smaller in men carrying the HD mutation than men without it.
On average, males had larger absolute
volumes than females in the
intracranial space (12 %; > 14,000 brains),
total brain (11 %; 2,523 brains), cerebrum (10 %; 1,851 brains), grey matter (9 %; 7,934 brains), white matter (13 %; 7,515 brains), regions filled with cerebrospinal fluid (11.5 %; 4,484 brains), and cerebellum (9 %; 1,842 brains).
In contrast, right, left, and
total lateral ventricles were proportionally larger than controls, after adjustment for
intracranial volume.