Sentences with phrase «toward human clinical»

More animal studies would be needed to move this drug toward human clinical trials, but «what we hope is that we could use this drug to intervene in patients who have had an episode of prolonged seizures and give it to them briefly following that episode to protect them from becoming epileptic,» said James McNamara, M.D., a professor in the departments of neurobiology and neurology at Duke University.

In a mechanism that Tan hopes will become common, his group will now hand off this rational combination to other researchers at the CU Cancer Center and elsewhere who will move the drugs toward a human clinical trial.

The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical trials.

Not exact matches

The recent funding will be used toward building out Kallyope's gut - brain axis platform and getting one of Kallyope's programs near or into human clinical trials.

We have more confidence that we can move toward clinical use of these cells in humans with less concern than we've previously had.»

«The ultimate goal of this research will be to advance HIF - 1alpha stabilizers toward clinical trials in humans, using versions of the drug that can be taken orally and reach the urinary tract,» Nizet said.

Together these data will support future efforts to conduct Phase I clinical trials in humans and constitute significant progress on the pathway toward a vaccine for falciparum malaria.

In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.

Based on their success to date in models of glaucoma, the researchers are making significant steps toward moving into human testing and validation of a biomarker for clinical use.

Getting the patent on the molecule is a major step toward doing clinical studies in humans.

The Mental Research Institute is a small, independent, multi-disciplinary, non-profit corporation: devoted to conducting and encouraging scientific research based on new ways of looking at how people interact dedicated to benefit the human community worldwide through its publications, education and training, clinical and consultative services committed to extending our tradition of innovation and openness toward new interactional paradigms of change.