Sentences with phrase «toxic at high doses»

Nutrients generally deliver their greatest benefits when the body is deficient in them; few benefits when the body is replete; and often become toxic at high doses.

This would help tamp down antibiotic resistance, while allowing doctors to lower the dosage of antibiotics that are toxic at high doses and that produce nasty side effects such as deafness and kidney damage.

Not exact matches

The toxic effects started very soon after PTCs were exposed to HEC, and further increased at higher doses.

New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that's used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline.

«Using a mouse model of tuberculosis, we have shown lower doses of bedaquiline together with verapamil have the same antibacterial effect as the higher toxic doses,» says Shashank Gupta, Ph.D., a research fellow at Johns Hopkins.

All drugs can be toxic at sufficiently high doses, Kay emphasizes.

The application of ActD at high doses (> 800 nM) is limited due to its high toxicity through acting as a transcription blocker; however at low doses (10 - 100 nM) it induces p53 expression and is not highly toxic [13, 14].

DNA interstrand crosslinks (ICLs) are highly toxic DNA lesions that can form endogenously but are also induced at high doses in cancer chemotherapy.

Where traditional toxicology asserts that higher doses does greater harm, bisphenol A tests show that low doses can be the most toxic of all, partly because at low levels it can fall below the radar of your body's natural detox mechanism.

Many studies have shown that at high doses, vitamin C is toxic to cancer cells, able to work synergistically with conventional therapies such as chemotherapy and radiation.

Vitamin A at high doses can be toxic to the body, but it is added into this product at a safe dose of 5000 IU.

Cyanocobalamin at high doses has never been shown to be toxic.

According to the study, «High doses of free fructose have been proven to literally punch holes in the intestinal lining allowing nasty byproducts of toxic gut bacteria and partially digested food proteins to enter your bloodstream and trigger the inflammation that we know is at the root of obesity, diabetes, cancer, heart disease, dementia, and accelerated aging.»

(Note: the right dose of these nutritional supplements should be established in consultation with the veterinarian, since some of them — namely vitamin A, selenium and iron — can be toxic when given at relatively high levels).

The toxic dose is dependant on weight, so little dogs are at higher risk, but with the higher levels of cocoa in chocolate products now even bigger dogs are at risk.

They have virtually no toxic side effects, even at high doses, and can be used in patients ranging from pocket pets to dogs, cats, birds and even horses.

Cyclophosphamide use may increase the risk of bladder cancer later in your pet's life Unneutered males male develop sterility Toxic to the heart at high doses Lung damage is possible If you notice any of these symptoms or anything else unusual, contact your veterinarian Can this drug be given with other drugs?

Liver cell destruction (hepatocellular necrosis), ingestion of toxic products, tainted foods or medications (such as giving Tylenol to cats, medications at too high a dose or a unique reaction to a medication that your veterinarian could not have predicted), lack of liver blood supply (hepatic hypoxia), congestive heart failure and bile duct obstruction can all cause elevated GDH levels in your pet.

«Chocolate, especially chocolate with a high cocoa content, contains theobromine, which can be toxic to heart and can induce seizures or pancreatitis at high doses,» explains Dr. Wismer.