Prior and her colleagues say that several cellular processes known to be associated with Alzheimer's pathology are affected by J147, including an increase in a protein called brain - derived neurotrophic factor (BDNF), which protects neurons
from toxic insults, helps new neurons grow and connect with other brain cells, and is involved in memory formation.
miR - 126 regulates growth factor activities and vulnerability to
toxic insult in neurons.
And the injury is from uncontrolled oxidative stress, which results
from toxic insults, infections, allergens, stress and just eating too much poor quality food.
We should think of alcohol as
a toxic insult.
After adding a substance that causes digestive problems, the researchers said that the mice with a higher ability to bind ICZ to the AHR were protected from a chemical that induced digestive problems, but the mice with the lower affinity suffered from
the toxic insult.
By placing aSyn and the huntingtin protein into the library separately and then monitoring each cell's reaction, they were able to deduce which genes are important for the cells to survive
the toxic insult from aSyn, and which ones are needed to help the cells survive the huntingtin protein.
Additionally, saturated fat has been shown to protect the liver from
the toxic insults of alcohol and medications, including acetaminophen and other drugs commonly used for pain and arthritis, such as nonsteroidal anti-inflammatory drugs or NSAIDs, and even to reverse the damage once it has occurred.
Understanding how to optimize our mitochondria (energy factories) and how to reduce oxidative stress (which results from
toxic insults, infections, allergens, stress, and just eating too much poor quality food) is an often overlooked yet vital component to becoming a thriving human.