«It could be due to
toxic side effects of drugs, doctors» prescribing practices, patients» misuse of prescription drugs, reasons related to pharmaceutical industry's marketing strategies or some combination of these factors,» he said.
Not exact matches
Companies like U.S. biotech giant Gilead and the U.K.'s GlaxoSmithKline (the majority stakeholder in global HIV partnership ViiV Healthcare) have developed
drugs that drastically lower the chance
of HIV infection — or which simply lower the number
of drugs you have to take to treat it, consequently curbing the risk
of toxic side effects while simplifying medical regimens.
Not all chemotherapy
drugs are equally effective for all people, and finding the best treatment for an individual is a painful process
of trial and error that wastes time and exposes patients to
toxic side effects.
They found that their method reduced the amount
of the
drug that was found in the liver, spleen and kidneys and reduced the
drugs»
toxic side -
effects.
Even as undoubtedly useful a
drug as penicillin probably wouldn't be approved today, because
of the (albeit low) frequency
of toxic side effects.
Sometimes,
toxic side effects aren't discovered until fairly late in the
drug development process, when substantial amounts
of time and money have already been invested in clinical trials.
A team
of researchers at the University
of Georgia has developed a non-invasive method
of delivering
drugs directly to cancerous tissue using magnetic forces, a form
of treatment that could significantly reduce the
toxic side effects of chemotherapy.
As a result, physicians should be able to up the concentration
of the
drug without worrying about
toxic side effects, says Jeffrey Hrkach, senior vice-president at BIND.
Toxic side -
effects of a
drug used to treat liver cancer could be reduced with a filtration system developed by surgeons in the US.
In February a group
of researchers from Case Western Reserve University reported online in Science that a cancer
drug with relatively benign
side effects was able to rapidly clear from the brains
of mice
toxic amyloid - beta protein fragments that accompany Alzheimer's.
We have known for a while that microRNAs are important in cancer, but their diversity
of roles has meant it's been difficult to target them with
drugs without causing
toxic side -
effects.
Thanks to the participation
of patients in Sweden, Spain, France and Germany, we can now predict the risk
of suffering a serious
side -
effect of medication against
toxic goitre,» says Pär Hallberg, chief physician and associate professor at Clinical Chemistry and Pharmacology, Uppsala University Hospital (Akademiska sjukhuset) who also set up the European
Drug Induced Agranulocytosis Consortium (EUDAC).
«The way the
drug works means that we would need to be sure it was being used against the cold virus, and not similar conditions with different causes, to minimize the chance
of toxic side effects,» Tate said.
In the treatment
of intestinal protozoan infections...
drugs are generally so
toxic that they can not be administered for prolonged periods
of time, whereas GSE can be administered for weeks or months; prolonged treatment being essential for the cure
of chronic protozoan infections... I have had some immunosuppressed patients taking the preparation for over a year with no apparent development
of side effects or
drug resistance.»
And people taking these new generations
of drugs experience more
toxic side effects than plain old penicillin ever brought them.
There are a whole host
of parasite prevention
drugs, unfortunately they are all full
of toxic chemicals which can cause nasty
side effects and even long term health problems.
Higher dose
of drugs may increase the
toxic side effects to a greater extent than the increase in beneficial
effects.
Today, newer
drugs are available that do not have these
toxic side effects, and as a result, we are able to successfully treat more than 95 percent
of canine heartworm infections.
Potential new agents are also being investigated that it is hoped will overcome limitations
of the current options, which include a narrow antiviral spectrum, ineffectiveness against latent virus infections, development
of drug - resistance and
toxic side effects.