Sentences with phrase «toxicity studies»

Note that toxicity studies of medication usually require treatment with huge doses over periods of time involving most or all of the animal's lifetime.

Animal toxicity studies have shown it's as safe as pure water, and there are no reported allergic responses to it in the medical literature.

Glaza, SM, «Acute oral toxicity study of BioCell collagen II ™ in rats,» Covance Laboratories.

The level, which is based on toxicity studies in rabbits, will allow regulators to better assess levels of glyphosate in food and other sources, the agency says.

Oral acute toxicity studies in rats indicated an LD50 greater than 4,640 mg / kg.

C188 - 9 was administered at the maximum tolerated daily dose (100 mg / kg BW) based on drug toxicity studies carried out in mice by Dr David J Tweardy.

Her team placed adult fathead minnows (Pimephales promelas)-- fish commonly used in aquatic toxicity studies — in aquaria containing 0.01 - 0.5 micrograms per litre (0.01 - 0.5 parts per billion) of various mixtures of these chemicals.

Acute toxicity studies showed no oral toxicity of J147 in mice at the maximum testable dose of 2 gm / kg and other safety tests including hERG, CYP450 inhibition and Ames were also negative which further supports the safety of J147.

Following a consultation EFSA maintains the requirement for an extended one generation reproductive toxicity study for substances added intentionally to infant formula.

Calls for new toxicity study guidelines to more fully protect honeybees; a reevaluation of neonicotinoids and neonicotinoid seed treatments; assessment of other pesticides for their potential impacts on pollinators; restrictions on the use of pesticides that are acutely toxic to bees; reduced exposure during planting of pesticide - treated seed; and expedited review of Varroa mite control products.

Das explained that short term toxicity studies in mice show the compounds are well tolerated.

Hyalella azteca are invertebrates that are widely used for sediment and water toxicity studies.

A NIH National Cooperative Drug Discovery / Development grant funded the early basic science and discovery of this investigational drug and the Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute helped support some of the key toxicity studies that FDA required, Conn said.

Sakuma S, Kumagai H, Shimosato M, Kitamura T, Mohri K, Ikejima T, Hiwatari KI, Koike S, Tobita E, McClure R, Gore JC and Pham W. Toxicity studies of coumarin 6 - encapsulated polystyrene nanosphere conjugated with peanut agglutinin and poly (N - vinylacetamide) as a colonoscopic imaging agent in rats.

He also oversees the design and execution of GLP toxicity studies, a critical final step before IDRI's vaccines can be tested for safety and efficacy in humans.

Current toxicity studies indicate its LD50 (dose at which 50 percent of the tested animals perish) is about 28.6 ml / kg, or about 3,360 mg / kg.

A very detailed acute oral toxicity study conducted by Covance laboratories confirms its safety.20

«We hope this will expand the use of organs - on - chips in a variety of contexts, including drug screening and drug toxicity studies,» adds Khademhosseini.

Goss studied Daphnia magna, a tiny freshwater crustacean used in many aquatic toxicity studies.

«Wheat gets boost from purified nanotubes: Toxicity study shows plant growth enhanced by — but only by — purified nanotubes.»

A 91 - day subchronic toxicity study was conducted in male and female Sprague - Dawley rats following FDA Redbook protocols.

Out of concern for our customers and our concern for safety as a whole, we had a toxicity study performed based on the highest levels of tungsten found in our rice protein drinks.

Although we know our rice protein is safe for consumption based on our toxicity study, we are continuing to test and look into better sourcing.

Quaternary ammonium compounds were introduced in the 1950s and 1960s before the standardization of toxicity studies.

Chemical manufacturers conducted some toxicity studies on the compounds during this period, but they were never published.

But overall, the resulting toxicity of the wastewater due to its silver content was negligible to zebrafish embryos — a model animal used in toxicity studies.

While past studies have analyzed kidney tubular cells cultured under flow conditions in vitro, this is the first report of a toxicity study using primary human kidney proximal tubular epithelial cells in a microfluidic «organ - on - a-chip» microdevice.

Also, Appendix C contains «toxicity studies» — this section makes up 21 pages of the 857 pages of text (not including table of contents or index).

Argentyn 23 also recently completed a murine Acute Oral Toxicity Study (LD50) with Covance Laboratories, Inc., (ref: 24742 -0-800).

Toxicity studies of Blockol, a dietary supplement containing Phase 2 starch neutralizer (Phase 2), a standardized extract of the common white kidney bean (Phaseolus vulgaris)

Safety of maropitant in dogs was demonstrated in a three - month oral toxicity study and a two - week pharmacokinetics study that demonstrated maropitant concentrations reached steady state after approximately four days following 2 mg / kg / day oral administration.1