Sentences with phrase «toxicity studies in»

Oral acute toxicity studies in rats indicated an LD50 greater than 4,640 mg / kg.

The level, which is based on toxicity studies in rabbits, will allow regulators to better assess levels of glyphosate in food and other sources, the agency says.

Das explained that short term toxicity studies in mice show the compounds are well tolerated.

Not exact matches

It's then followed by toxicity and allergenicity studies, in the form of either experiments or evidence from the scientific literature.

High dosages of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another study using rats and humans demonstrated lack of reproductive toxicity.

The author of the study, T. Glinsukon, concluded that the acute toxicity of capsaicinoids as a food additive in mankind was negligible.

In a study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal toxicity in rats: Beneficial role of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers of rats who were also fed repeatedly heated palm kernel oiIn a study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal toxicity in rats: Beneficial role of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers of rats who were also fed repeatedly heated palm kernel oiin rats: Beneficial role of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers of rats who were also fed repeatedly heated palm kernel oiin Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers of rats who were also fed repeatedly heated palm kernel oil.

Because the toxicity is associated with oxidative stress and inflammation, the study explored antioxidant and anti-inflammatory effect of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.

At present, there have been no studies on allergenicity and toxicity of Golden Rice, which should be first established in animal feeding trials before feeding trials on humans commence.

A Canadian study published this year around the same time titled «Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways» observed that coconut oil and its medium chain fatty acids (MCFAs) protect against amyloid beta (Aβ) induced neurotoxicity in primary rat cortical neurons.

The author of the study, T. Glinsukon, concluded that the acute toxicity of capsaicinoids as a food additive in mankind was neglible.

Out of concern for our customers and our concern for safety as a whole, we had a toxicity study performed based on the highest levels of tungsten found in our rice protein drinks.

As to «toxic» chemicals, show me one study that establishes a real - world link between diapers and wipes and toxicity in a living creature.

On Tuesday, Environmental Conservation Commissioner Basil Seggos urged Judith Enck, regional administrator of the U.S. Environmental Protection Agency, to drastically beef up her plans to study remaining PCB toxicity levels in the river in the aftermath of a six - year dredging project by General Electric Co..

Quaternary ammonium compounds were introduced in the 1950s and 1960s before the standardization of toxicity studies.

In January, a study by European researchers tied genetically modified corn created by Monsanto to toxicity in the kidney and liver, resulting in hyperbolic headlines about the danger of GM foodIn January, a study by European researchers tied genetically modified corn created by Monsanto to toxicity in the kidney and liver, resulting in hyperbolic headlines about the danger of GM foodin the kidney and liver, resulting in hyperbolic headlines about the danger of GM foodin hyperbolic headlines about the danger of GM foods.

I wanted to follow up this research, to look at how silicon reduces aluminium toxicity in different maize genotypes and to study the role of compounds released by roots in mechanisms of metal tolerance.

«We hope this will expand the use of organs - on - chips in a variety of contexts, including drug screening and drug toxicity studies,» adds Khademhosseini.

The pharmacologist felt the animal studies submitted were not a good indication of possible toxicity in humans, since animals absorb thalidomide poorly.

In the present study, researchers of Kanazawa University, Japan, attacked this problem; they succeeded in reducing the toxicity to microorganisms by developing a novel solvent, a carboxylate - type liquid zwitterion * 1, for dissolving biomass cellulosIn the present study, researchers of Kanazawa University, Japan, attacked this problem; they succeeded in reducing the toxicity to microorganisms by developing a novel solvent, a carboxylate - type liquid zwitterion * 1, for dissolving biomass cellulosin reducing the toxicity to microorganisms by developing a novel solvent, a carboxylate - type liquid zwitterion * 1, for dissolving biomass cellulose.

She describes her project as studying hyperthermophilic archaea, the living occupants of deep - sea hydrothermal vents that survive in extreme heat, pressure, and chemical toxicity.

There I studied the factors that limit the growth of plants on different acid soils, and in particular, the ways in which plants have adapted to hydrogen or aluminium toxicity.

Additionally, I predict that at the completion of our study, despite the higher doses given per treatment in the experimental accelerated, hypofractionated RT arm, there will be no increased toxicity with this regimen.

Dr. McCabe said nanoparticles are a leading - edge technology also being studied for delivery of drugs for other conditions, such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and side effects of those medications and to make them more effective.

«In the case of pharmaceuticals, the onus is on the pharmaceutical company to do the research with toxicity testing, randomized control trials and post-exposure observational studies,» Conry said.

The drug was not associated with severe toxicity in this or other recent studies.

Even in a seemingly implausible accidental - release scenario in which all of a well's hydraulic fracturing fluid and untreated wastewater were discharged directly into surface waters for the lifetime of the well, shale - gas electricity had a lower lifetime human toxicity impact, or HTI, than coal electricity, according to the study.

In preliminary experiments with mice, the study also demonstrates the absence of an immune response and low toxicity.

Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of human kidney development and toxicity.

The methanotrophs identified in this study «open new opportunities to explore how nature detoxifies methylmercury and could improve our prediction of mercury toxicity levels and support better risk assessments and remediation efforts at mercury contamination sites,» Gu added.

The first studies of BPA toxicity in the 1980s tested rats at high levels of exposure (50 milligrams of BPA per kilogram of body weight per day).

«The efficacy and toxicity need to be validated in clinical studies, but I think the potential is there.»

This tumor - targeted action of isoprenoids was manifested in animal studies showing no toxicity of isoprenoids at tumor - suppressive doses (reviewed by Mo & Elson, Exp Biol Med, 2004, 229:567 - 85).

«The beauty of this study is that we were able to inhibit tumor growth in mice without toxicity.»

Just a few weeks ago, WHO said that using any of the experimental drugs or vaccines in the pipeline simply wasn't in the cards, because none of them have been through a phase I clinical study, the type of trial in which medical products are tested on healthy volunteers to study their toxicity.

However, few studies have investigated iron toxicity in reptiles, and no one knows what levels might cause liver damage in alligators.

Ami Zota, an epidemiologist at University of California, San Francisco who did not participate in the Salinas study, said the findings are «important to our understanding of PBDE toxicity in humans as well as to our understanding of thyroid disruption during pregnancy.»

«Future studies will need to very carefully investigate and access the toxicity of titanium suboxide nanoparticles in the human lung, and this could take years, a sobering thought considering its potential danger,» Hochella said.

Results from this study will aid in future investigations of the fate, risk and toxicity of CECs in landfill leachate.

But overall, the resulting toxicity of the wastewater due to its silver content was negligible to zebrafish embryos — a model animal used in toxicity studies.

The researchers looked at first - trimester exposures to ARVs in a group of 2,580 HIV - exposed, uninfected children enrolled between 2007 and 2012 in an ongoing U.S. study that follows HIV - infected pregnant women and their children — the Pediatric HIV / AIDS Cohort Study (PHACS) Surveillance Monitoring of ART Toxicities (SMARTT) sstudy that follows HIV - infected pregnant women and their children — the Pediatric HIV / AIDS Cohort Study (PHACS) Surveillance Monitoring of ART Toxicities (SMARTT) sStudy (PHACS) Surveillance Monitoring of ART Toxicities (SMARTT) studystudy.

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

In the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in OncotargeIn the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in Oncotargein Oncotarget.

This study, «Final Results of Local - Regional Control and Late Toxicity of RTOG 9003: A Randomized Trial of Altered Fractionation Radiation for Locally Advanced Head and Neck Cancer,» is a multi-institutional, randomized Phase III trial of fractionation in locally advanced head and neck cancer.

«This study, one of only a few large studies to have follow - up beyond five years, demonstrates that patients who have head and neck cancers and who are being treated with radiation therapy alone have improved local - regional control and no increase in late toxicity when radiation therapy is delivered twice a day in two smaller doses which we call hyperfractionation,» said Jonathan J. Beitler, MD, MBA, FASTRO, lead author of the study and professor of radiation oncology, otolaryngology and hematology / medical oncology at the Winship Cancer Institute of Emory University School of Medicine in Atlanta.

Goss studied Daphnia magna, a tiny freshwater crustacean used in many aquatic toxicity studies.

«Free online access to millions of documents on chemical toxicity made possible through ToxicDocs: A new special issue discusses the history, impact and case studies of an online database of information about the dangers of toxic substances in products.»

Production of some compounds in this family of environmentally persistent chemicals — associated with liver toxicity, reduced fertility and a variety of other health problems in studies of people and animals — has been phased out in the United States and many other nations.

«We need to develop specific tools to study chemical toxicity in human reproductive cells; this will allow us to accurately assess safety thresholds for different compounds, and re-evaluate the acceptible daily intake levels to protect human health for some of them» said Professor Habert.

In other research published in the Journal of Hazardous Materials («Investigation of acute effects of graphene oxide on wastewater microbial community: A case study»), investigators determined that the toxicity of GO was dose dependent and was toxic in the range of 50 to 300 mg / In other research published in the Journal of Hazardous Materials («Investigation of acute effects of graphene oxide on wastewater microbial community: A case study»), investigators determined that the toxicity of GO was dose dependent and was toxic in the range of 50 to 300 mg / in the Journal of Hazardous Materials («Investigation of acute effects of graphene oxide on wastewater microbial community: A case study»), investigators determined that the toxicity of GO was dose dependent and was toxic in the range of 50 to 300 mg / in the range of 50 to 300 mg / L.