Toxicity studies of Blockol, a dietary supplement containing Phase 2 starch neutralizer (Phase 2), a standardized extract of the common white kidney bean (Phaseolus vulgaris)
Sakuma S, Kumagai H, Shimosato M, Kitamura T, Mohri K, Ikejima T, Hiwatari KI, Koike S, Tobita E, McClure R, Gore JC and Pham W.
Toxicity studies of coumarin 6 - encapsulated polystyrene nanosphere conjugated with peanut agglutinin and poly (N - vinylacetamide) as a colonoscopic imaging agent in rats.
Note that
toxicity studies of medication usually require treatment with huge doses over periods of time involving most or all of the animal's lifetime.
Acute and subacute
toxicity study of 1,8 - cineole in mice Antimicrobial activity of essential oils and other plant extracts In Vitro Antibacterial Activity of Essential Oils against Streptococcus pyogenes In vitro antibacterial activity of some plant essential oils A near fatal case of high dose peppermint oil ingestion - Lessons learnt National Association for Holistic Aromatherapy Data Safety Sheet for Essential Oils during pregnancy International Association of Professional Aromatherapists Pregnancy Data Sheet (PDF) Robert Tisserand
Thirteen - week oral
toxicity study of branched - chain amino acids in rats.
A 13 - week subchronic
toxicity study of chitin in F344 rats.
Not exact matches
It's then followed by
toxicity and allergenicity
studies, in the form
of either experiments or evidence from the scientific literature.
High dosages
of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another
study using rats and humans demonstrated lack
of reproductive
toxicity.
The author
of the
study, T. Glinsukon, concluded that the acute
toxicity of capsaicinoids as a food additive in mankind was negligible.
In a
study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal
toxicity in rats: Beneficial role
of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers
of rats who were also fed repeatedly heated palm kernel oil.
Because the
toxicity is associated with oxidative stress and inflammation, the
study explored antioxidant and anti-inflammatory effect
of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.
At present, there have been no
studies on allergenicity and
toxicity of Golden Rice, which should be first established in animal feeding trials before feeding trials on humans commence.
A Canadian
study published this year around the same time titled «Coconut oil protects cortical neurons from amyloid beta
toxicity by enhancing signaling
of cell survival pathways» observed that coconut oil and its medium chain fatty acids (MCFAs) protect against amyloid beta (Aβ) induced neurotoxicity in primary rat cortical neurons.
The author
of the
study, T. Glinsukon, concluded that the acute
toxicity of capsaicinoids as a food additive in mankind was neglible.
Out
of concern for our customers and our concern for safety as a whole, we had a
toxicity study performed based on the highest levels
of tungsten found in our rice protein drinks.
Of the
studies that have been done, one or more
studies show reproductive effects at very low doses, organ system
toxicity, and developmental / reproductive
toxicity!
The FDA maintains that
studies using standardized
toxicity tests have shown BPA to be safe at the current low levels
of human exposure.
On Tuesday, Environmental Conservation Commissioner Basil Seggos urged Judith Enck, regional administrator
of the U.S. Environmental Protection Agency, to drastically beef up her plans to
study remaining PCB
toxicity levels in the river in the aftermath
of a six - year dredging project by General Electric Co..
Quaternary ammonium compounds were introduced in the 1950s and 1960s before the standardization
of toxicity studies.
In January, a
study by European researchers tied genetically modified corn created by Monsanto to
toxicity in the kidney and liver, resulting in hyperbolic headlines about the danger
of GM foods.
These mice have been followed for several more weeks with no signs
of toxicity, and Moderna has similar results from nonhuman primate
studies that they plan to publish soon, he says.
I wanted to follow up this research, to look at how silicon reduces aluminium
toxicity in different maize genotypes and to
study the role
of compounds released by roots in mechanisms
of metal tolerance.
«We hope this will expand the use
of organs - on - chips in a variety
of contexts, including drug screening and drug
toxicity studies,» adds Khademhosseini.
The pharmacologist felt the animal
studies submitted were not a good indication
of possible
toxicity in humans, since animals absorb thalidomide poorly.
In the present
study, researchers
of Kanazawa University, Japan, attacked this problem; they succeeded in reducing the
toxicity to microorganisms by developing a novel solvent, a carboxylate - type liquid zwitterion * 1, for dissolving biomass cellulose.
She describes her project as
studying hyperthermophilic archaea, the living occupants
of deep - sea hydrothermal vents that survive in extreme heat, pressure, and chemical
toxicity.
There I
studied the factors that limit the growth
of plants on different acid soils, and in particular, the ways in which plants have adapted to hydrogen or aluminium
toxicity.
Additionally, I predict that at the completion
of our
study, despite the higher doses given per treatment in the experimental accelerated, hypofractionated RT arm, there will be no increased
toxicity with this regimen.
Dr. McCabe said nanoparticles are a leading - edge technology also being
studied for delivery
of drugs for other conditions, such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce
toxicity and side effects
of those medications and to make them more effective.
«In the case
of pharmaceuticals, the onus is on the pharmaceutical company to do the research with
toxicity testing, randomized control trials and post-exposure observational
studies,» Conry said.
Researchers say further
study is needed using individual patient - level data among men with high risk prostate cancer to assess the benefit
of HRT and whether treatment
toxicity, particularly those to the bladder and urinary system are also low with HRT.
Even in a seemingly implausible accidental - release scenario in which all
of a well's hydraulic fracturing fluid and untreated wastewater were discharged directly into surface waters for the lifetime
of the well, shale - gas electricity had a lower lifetime human
toxicity impact, or HTI, than coal electricity, according to the
study.
After a series
of studies confirmed the activity and lack
of toxicity, Lee sent double - blinded samples
of the compound and control to a colleague at the BSL - 4 lab at the University
of Texas Medical Branch at Galveston who tested it against Nipah, Ebola and other viruses.
The findings suggest that as the U.S. energy market continues to shift from coal to natural gas, the overall «
toxicity burden»
of the electricity sector will decrease, said
study corresponding author Shelie Miller, an environmental engineer and an associate professor at the U-M School for Environment and Sustainability's Center for Sustainable Systems.
For the hydraulic fracturing system, the
study estimated the
toxicity of the fracturing fluid chemicals used to crack rock and release natural gas, as well as the wastewater associated with shale - gas extraction.
«This research
study clearly demonstrates the anticancer potential
of omega - 3 fatty acids,» he said, adding that while the
study showed significant cancer cell
toxicity, it is too soon to tell whether the approach is able to kill every cancer cell.
In preliminary experiments with mice, the
study also demonstrates the absence
of an immune response and low
toxicity.
The level, which is based on
toxicity studies in rabbits, will allow regulators to better assess levels
of glyphosate in food and other sources, the agency says.
Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to
study mechanisms
of human kidney development and
toxicity.
The methanotrophs identified in this
study «open new opportunities to explore how nature detoxifies methylmercury and could improve our prediction
of mercury
toxicity levels and support better risk assessments and remediation efforts at mercury contamination sites,» Gu added.
The first
studies of BPA
toxicity in the 1980s tested rats at high levels
of exposure (50 milligrams
of BPA per kilogram
of body weight per day).
This tumor - targeted action
of isoprenoids was manifested in animal
studies showing no
toxicity of isoprenoids at tumor - suppressive doses (reviewed by Mo & Elson, Exp Biol Med, 2004, 229:567 - 85).
«Further prospective
studies are warranted for teens between 10 and 18 years
of age to determine the most appropriate Vancomycin dosing to maximize drug efficacy and reduce the risk
of Vancomycin induced renal
toxicity.»
«Until this
study, the
toxicity of thirdhand smoke has not been well understood,» Hang said.
A new
study shows that for ladybirds, the brightness
of their color reveals the extent
of their
toxicity to predators.
However, the efficacy and potential
toxicity of botanicals are still being
studied.
«The beauty
of this
study is that we were able to inhibit tumor growth in mice without
toxicity.»
Just a few weeks ago, WHO said that using any
of the experimental drugs or vaccines in the pipeline simply wasn't in the cards, because none
of them have been through a phase I clinical
study, the type
of trial in which medical products are tested on healthy volunteers to
study their
toxicity.
Ami Zota, an epidemiologist at University
of California, San Francisco who did not participate in the Salinas
study, said the findings are «important to our understanding
of PBDE
toxicity in humans as well as to our understanding
of thyroid disruption during pregnancy.»
«Future
studies will need to very carefully investigate and access the
toxicity of titanium suboxide nanoparticles in the human lung, and this could take years, a sobering thought considering its potential danger,» Hochella said.