TREM2 levels could therefore be a biomarker used to
track immune activity while Alzheimer's is progressing, irrespective of whether the disease is genetic or not.
Not exact matches
After initiating photoreceptor loss in the fish retinas, the researchers monitored the
immune system's response by
tracking the
activity of three types of fluorescently labeled
immune cells in and around the eye: neutrophils, microglia and peripheral macrophages.
Zebrafish larvae and fluorescently marked
immune cells allow researchers to
track immune system
activity in a model of retinal degeneration.
Monitoring
immune cell
activity — including phenotyping
immune cell subsets,
tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of
immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the
immune system.
Researchers at the Cells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the
activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of
immune cells, then increasing their numbers in a test tube and finally
tracking them spatially and temporally in living organisms.