Zebrafish larvae and fluorescently marked immune cells allow researchers to
track immune system activity in a model of retinal degeneration.
Not exact matches
After initiating photoreceptor loss in the fish retinas, the researchers monitored the
immune system's response by
tracking the
activity of three types of fluorescently labeled
immune cells in and around the eye: neutrophils, microglia and peripheral macrophages.
Monitoring
immune cell
activity — including phenotyping
immune cell subsets,
tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of
immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the
immune system.