Cytology detected upper
tract urothelial cancers in only 10 percent of those patients.
AA is implicated in multiple cancer types, sometimes with very high mutational burdens, especially in upper
tract urothelial cancers (UTUCs).
Of 56 patients with upper
tract urothelial cancer, 75 percent tested positive using UroSEEK, including 79 percent of those with noninvasive tumors.
UroSEEK uses urine samples to seek out mutations in 11 genes or the presence of abnormal numbers of chromosomes that would indicate the presence of DNA associated with bladder cancer or upper
tract urothelial cancer (UTUC).
Research Interests: bladder cancer; upper
tract urothelial cancer; epigenetics; chromatin; histones; methylation; drug response; drug resistance; urology
Not exact matches
I am a urologic oncologist and surgeon - scientist focused on using modern scientific tools to improve the management of
urothelial cancers of the bladder and upper
tract.