The bacterium developed resistance to
the traditional drugs in as little as three days.
Not exact matches
Traditional drug giants have caught on to the not - so - dirty little secret that outsourcing
drug research (and
in - licensing) may be a more effective strategy than trying to create groundbreaking new molecules within the confines of a single lab.
With its
traditional insulin treatments
in the firing line due to U.S. price pressure, Novo Nordisk is pinning hopes for growth on new obesity
drugs and a once - weekly injection and tablet version of its semaglutide
drug.
The
Drug Enforcement Administration reports a sharp decline in bulk cash smuggling in 2016, which is the traditional payment method for drug shipments, and suggests that payments may have shifted toward cryptocurrencies, according to
Drug Enforcement Administration reports a sharp decline
in bulk cash smuggling
in 2016, which is the
traditional payment method for
drug shipments, and suggests that payments may have shifted toward cryptocurrencies, according to
drug shipments, and suggests that payments may have shifted toward cryptocurrencies, according to Lee.
This is far more targeted than the
traditional model for
drug development, which includes such scattershot methods as screening natural elements like soil from a plateau
in Norway and then asking, What might this do?
Several regional grocers fit the
traditional profile of an attractive target, but Shoppers
Drug Mart stood out as a uniquely strategic asset
in a less familiar but complementary space.
However, the prosecutor, US attorney Serrin Turner, said he found little to no distinction between the actions of both Shrem and Faiella, arguing that both crimes led to serious
drug trafficking; that he was «moving
drug money - not
in the
traditional way - online - but moving it nevertheless».
However,
in very rare circumstances, Ionis Pharmaceuticals is able to make an experimental
drug that we are developing available for patients outside of a
traditional clinical trial under an expanded access protocol, sometimes referred to as a treatment protocol.
Ligand isn't like a
traditional biotech stock
in that it doesn't spend years or decades bringing
drugs from the discovery stage to pharmacy shelves, which is an exceptionally risky boom - or - bust model.
Clinebell begins this particular work with definitions of addiction and alcoholism: «
In traditional psychiatric usage, the term addiction is limited to obsessive - compulsive abuse of substances like alcohol and
drugs....
Drug is a dialectal variant that appears in many areas of the U.S. Though drug is common in these areas and can not be considered wrong, it might be seen as out of place in more formal writing, where the traditional dragged is always the safer cho
Drug is a dialectal variant that appears
in many areas of the U.S. Though
drug is common in these areas and can not be considered wrong, it might be seen as out of place in more formal writing, where the traditional dragged is always the safer cho
drug is common
in these areas and can not be considered wrong, it might be seen as out of place
in more formal writing, where the
traditional dragged is always the safer choice.
Those same MPs who have for decades supported the Misuse of
Drugs Act, that piece of arcane and ineffective legislation which outlaws the more «traditional» drugs - cannabis, cocaine, heroin, MDMA, etc - in every sense from personal use and possession all the way up to production, are now suddenly concerned with criminalising u
Drugs Act, that piece of arcane and ineffective legislation which outlaws the more «
traditional»
drugs - cannabis, cocaine, heroin, MDMA, etc - in every sense from personal use and possession all the way up to production, are now suddenly concerned with criminalising u
drugs - cannabis, cocaine, heroin, MDMA, etc -
in every sense from personal use and possession all the way up to production, are now suddenly concerned with criminalising users.
The party is
in favour of reform of
traditional British institutions such as the Church of England, a change
in the electoral system from first - past - the - post to proportional representation, and
drug decriminalisation.
The psychoactive substances bill sought to crack down on legal highs — especially the new generation of
drugs that are designed to mimic the effects of
traditional illicit substances such as cannabis and ecstasy — which the Home Office says caused 129 deaths
in 2015.
As promised, the Motion was listed on the Order Paper and debated on the floor of plenary and the following resolutions were reached amongst which are; Mandate its Joint Committee on
Drugs and Narcotics and health to investigate the growing menace of cough and other prescriptive drugs abuse; Urge the FG to partner with stakeholders, traditional rulers, Pharmacists councils, NGOs to create framework in fighting this category of drug abuse and urge NAFDAC to embark on a vigorous sensitization campaign on the dangers of drug abuse and steps on achieving a successful rehabilitation for people with the addic
Drugs and Narcotics and health to investigate the growing menace of cough and other prescriptive
drugs abuse; Urge the FG to partner with stakeholders, traditional rulers, Pharmacists councils, NGOs to create framework in fighting this category of drug abuse and urge NAFDAC to embark on a vigorous sensitization campaign on the dangers of drug abuse and steps on achieving a successful rehabilitation for people with the addic
drugs abuse; Urge the FG to partner with stakeholders,
traditional rulers, Pharmacists councils, NGOs to create framework
in fighting this category of
drug abuse and urge NAFDAC to embark on a vigorous sensitization campaign on the dangers of
drug abuse and steps on achieving a successful rehabilitation for people with the addiction.
He decried the disregard for the
traditional institution and the failure of the legal system over the years, saying that the situation had encouraged impunity, religious intolerance and massive abuse of
drugs leading to insecurity
in many parts of the country.
According to a report from the National Cancer Institute, a study of 30 randomized studies found that THC (the active ingredient
in marijuana) extracts outperformed
traditional anti-nausea
drugs and helped patients gain weight.
Haro Hartounian, a specialist
in drug - delivery technologies at DepoTech
in San Diego, predicts that microspheres will prove more potent than
traditional booster shots and — by eliminating that second visit to the doctor — could lower the cost.
Drug candidates currently
in late stage clinical trials comprise of growth factors, which are
traditional protein - based biological
drugs associated with high costs, and some trials have been prematurely terminated.
Traditional genetic approaches together with the new wealth of genomic information for both human and model organisms open up strategies by which
drugs can be profiled for their ability to selectively kill cells
in a molecular context that matches those found
in tumors.
In managing diseases like cancer, for instance, he often subscribes to
traditional modalities offset by therapies that reduce a
drug's toxicity (and may also increase its effectiveness).
«Most parents today support
traditional health education topics like pregnancy prevention,
drug abuse and other risk behaviors that used to generate more debate
in years past.
If these peptides are developed for therapeutic use, the researchers anticipate that they could be used either
in stand - alone therapy or together with
traditional antibiotics, which would make it more difficult for bacteria to evolve
drug resistance.
NMP shares certain mechanistic similarities with other promising
drug candidates for myeloma that were discovered
in more
traditional ways.
In addition, the eCAPs worked just as effectively at killing Pseudomonas aeruginosa after it became resistant to the
traditional drugs.
The team challenged a highly infectious and pathogenic bacterium called Pseudomonas aeruginosa — which flourishes
in medical equipment, such as catheters, and causes inflammation, sepsis and organ failure — with both the
traditional drugs and eCAPs
in the lab.
Traditional antipsychotic
drugs, which have been used for 40 years, are known to alleviate symptoms of the disorder
in some patients by blocking receptors of dopamine, a neurotransmitter that is central to the brain's reward system as well as cognitive processing like attention and problem - solving.
Researchers recently investigated whether or not anti-TNFs, which help to control RA inflammation, would lower the risk and severity of heart attacks
in these patients compared to
traditional, non-biologic disease - modifying antirheumatic
drugs, or DMARDs.
Project 523 planned a three - pronged attack on
drug - resistant malaria: research and develop new
drugs the Western way, screen
traditional medicine and folk remedies to search for a Chinese therapy, and find ways to prevent malaria infection
in the first place.
In our platform, cells looked and acted like those that you would find in the body, showing more sensitive responses to drugs than traditional static culturing.&raqu
In our platform, cells looked and acted like those that you would find
in the body, showing more sensitive responses to drugs than traditional static culturing.&raqu
in the body, showing more sensitive responses to
drugs than
traditional static culturing.»
Drug development efforts based on harmine will need to grapple with its known psychoactive effects on the brain, which may explain its
traditional use
in spiritual ceremonies and as medicine.
The London Olympics mark the first summer games
in which the ABP will be
in use alongside
traditional drug screenings.
For their part, Carhart - Harris and his team are keen to study other types of psychedelic
drugs, including dimethyltryptamine (DMT), sometimes found
in a
traditional South American brew called ayahuasca.
The most important change occurring
in the industry is a shift away from the
traditional «big pharma» model for
drug development,
in which research and development are concentrated inside such companies as Pfizer, Merck, and AstraZeneca.
Also first -
in - class
drugs may not have an applicable comparator
drug, and
traditional follow - up studies may give inaccurate results if those who take a new
drug are different from those who took the comparator
drug.
The FDA needs to move beyond its
traditional focus on clinical studies about
drug effectiveness and side effects, and to seek public health data on potential abuse, the Academies advises
in its 400 - page proposal for targeting the deadly issue.
In the Philippines, fellow Maria Ruth B. Pineda will help set up a governance structure for the ASEAN - Network for
Drugs, Diagnostics, Vaccines, and
Traditional Medicines Innovation, an information - sharing initiative.
«From our past research, we know the ketogenic diet is effective
in approximately one - third of adults with epilepsy who are resistant to
traditional anti-seizure
drugs,» says Mackenzie C. Cervenka, M.D., associate professor of neurology and director of the Adult Epilepsy Diet Center at the Johns Hopkins University School of Medicine.
Findings of a three - year clinical trial led by University of Cincinnati (UC) transplant researchers suggest that a novel pre-operative
drug therapy reduces antibodies
in kidney patients with greater success than with
traditional methods, with the potential to increase the patients» candidacy for kidney transplantation and decrease the likelihood of organ rejection.
The results, published online and scheduled for the November print issue of JAMA Pediatrics, are particularly timely as the U.S. Food and
Drug Administration considers how to regulate e-cigarettes, which are easier for adolescents to purchase and,
in many respects, more attractive to young people than
traditional cigarettes.
Those were developed,
in part, as a byproduct of previous alliances
in which pharmaceutical companies payed for rights to develop would - be
drugs discovered at Scripps, as well as through the more
traditional approach of licensing early - stage compounds to startup companies that then raise money to develop them further.
The
drug — named mepolizumab — can replace
traditional, steroid - based treatments for a specific subset of patients, resulting
in improved outcomes and reduced side effects.
One option would be to shut down the expression of BCL11A, using small pieces of RNA,
in blood - forming stem cells that would then be given to a person with the disease; another would be to inhibit the action of BCL11A directly using a more
traditional, and possibly more practical, small - molecule
drug.
In French Pharmacist Finds Career Niche at Regulatory Agency, Elisabeth Pain, our contributing editor for south Europe, profiles French pharmacist Franck Diafouka, who worked in a handful of traditional pharmacy jobs before joining Europe's regulatory agency in charge of drug
In French Pharmacist Finds Career Niche at Regulatory Agency, Elisabeth Pain, our contributing editor for south Europe, profiles French pharmacist Franck Diafouka, who worked
in a handful of traditional pharmacy jobs before joining Europe's regulatory agency in charge of drug
in a handful of
traditional pharmacy jobs before joining Europe's regulatory agency
in charge of drug
in charge of
drugs.
In this new study, researchers also demonstrated that when they associate a PLK4 inhibitor with
traditional chemotherapy
drugs, they kill tumor cells with significantly lower
drug doses.
The test successfully identified
drugs in the samples, including fentanyl and its synthetic analogs, synthetic cannabinoids, and
traditional drugs such as methamphetamine and lorazepam.
New psychoactive substances have been associated with fatalities and severe injuries
in a number of cases
in the U.S. and have led investigators to rethink
traditional drug monitoring protocols.
«Over the past five to 10 years, types of illicit
drugs used around the world have been created or repurposed from research chemicals to mimic the effects of
traditional drugs of abuse
in order to circumvent legal control and detection,» explained corresponding author Sabra Botch - Jones, MS, MA, D - ABFT, forensic toxicologist and instructor
in the Biomedical Forensic Sciences program
in the department of anatomy and neurobiology at BUSM.
Tu also received numerous awards nationally which include «Award for Progress
in Anti-malarial Research Achieved by Project 523 Scientific Team» honored by China National Congress of Science and Technology (1978); «National Scientific Discovery Award» for Anti-malaria
Drug - Qinghaosu by the China Ministry of Science and Technology (1979); «Invention Award» (as the first inventor) by China National Congress for Awards
in Science and Technology (1982); «Award of Young and Middle - aged Experts with Outstanding Contribution» by the Chinese Government (1984); «The Top Honorary Award» by China Academy of
Traditional Chinese Medicine (1992); «The Top Ten National Achievements for Progress
in Science and Technology» by China National Committee of Science and Technology (1992); «First - Class Award of National Achievements
in Science and Technology» by China National Award Committee for Advances
in Science and Technology (1992); «National Model» by China State Council (1995); «Award for Outstanding Achievement
in Traditional Chinese Medicine» by Guangzhou Zhongjing Award Foundation for
Traditional Chinese Medicine (1995); «Outstanding Scientific Achievement Award» by Qiu Shi Science and Technologies Foundation of Hong Kong (1996); «Top Ten Health Achievements
in New China» by China Ministry of Health (1997); «Female Inventor of the New Century» by China National Bureau of Intellectual Property (2002); «Golden Medal of the 14th National Invention Exhibition» by China National Bureau of Intellectual Property (2003); «Award for Development of Chinese Materia Medica» by Cyrus Chung Ying Tang Foundation, (2009).
The side effects of immunotherapy are usually quite different from those of
traditional cancer
drugs used
in therapies such as chemotherapy.