Sentences with phrase «trafficking pathways»

His lab applies automated high - content screening microscopy to understand the regulation of membrane traffic pathways in mammalian cells.

His research focusses on the primary cilium, and specifically, the role of protein and membrane trafficking pathways in cilium formation, function and disease mechanisms.

The observation that loss - of - function mutations in DENND5A causes epileptic encephalopathy suggests that DENND5A protein controls membrane trafficking pathways critical for normal neuronal development and strengthens the argument that protein trafficking processes in cells are critical for normal neuronal development and function.

He hopes to pursue projects such as developing therapeutics with chemists, working with biophysicists to study protein conformational changes relevant to viral entry into the cell, and investigating cellular trafficking pathways relevant to the viral life cycle in collaboration with cell biologists.

Furthermore, the project will analyze the dynamics of these complexes between membrane and cytosol, the dynamics of their assembly and disassembly on endosomal and vacuolar subcompartments, and their connection to trafficking pathways like the AP - 3 pathway.

Here we discuss the peculiarities of the trafficking pathways of a variety of toxins, and how these may allow the toxins to be used as delivery vehicles for therapeutic and diagnostic purposes.

Urination is almost always sprayed on a vertical surface (wall or furniture) and in a prominent location (near doorway or high - traffic pathway).