Not exact matches
Given his
training in developmental biology, Raman focused the team to seek a novel drug target on
genes important to the development of
model organisms — fruit flies (Drosophila) and yeast (Saccharomyces cerevisiae)-- rather than on oncogenes that transform a normal cell into a cancer cell.
«We analyzed dozens of variants of this
gene and quantitatively measured expression in about 1,000 embryos, creating a quantitative data set that could be used to
train mathematical
models, utilizing parameter optimization,» Arnosti said.
Results We present an automated
gene prediction pipeline, Seqping that uses self -
training HMM
models and transcriptomic data.