Sentences with phrase «trait loci»

The identification of quantitative trait loci (QTL) for heat tolerance in the most promising donors and tagging these with molecular markers that could be used in selecting for the trait (s) could effectively offset the difficulty of screening cultivars in the field due to the unpredictability of heat stress occurrence during flowering.

Based on our (Todhunter et al., 2005; Zhu et al., 2008; Mateescu et al., 2008; Phavaphutanon et al., 2009; Zhou et al., 2010) and others (Chase et al., 2005; Marschall and Distl, 2007, 2012) research, between 10 and 20 quantitative trait loci (QTL) likely control hip dysplasia expression.

Four quantitative trait loci (QTL) have been identified through linkage mapping for cranial cruciate ligament disease in the Newfoundland breed (Wilke et al., 2009).

It relies on the assumption that the genetic markers in close proximity to causal or contributing mutations segregate with the trait loci; they are in linkage disequilibrium.

271/5: 30 Mapping expression quantitative trait loci to identify insulin resistance, obesity, and Type 2 diabetes genes in African Americans.

Saturday, Oct. 21, 11:20 - 11:40 a.m., South Hall B, South Building Featured Plenary Abstract: Massively parallel reporter assays combined with cell - type specific expression quantitative trait loci profiling identified a functional melanoma risk variant in HIV - 1 inhibitor gene, MX2 J. Choi, National Cancer Institute, et al

Linkage and quantitative trait loci (QTL) mapping were performed by combining our new genotypic data with a previously generated genetic map for this population, then adding rust disease data from our experiment to identify genomic regions associated with leaf rust resistance.

We have pioneered studies demonstrating that low - yielding wild and exotic Oryza species harbor genes and quantitative trait loci (QTL) that can be used to enhance the performance of modern, high - yielding rice cultivars.

Confirmation of quantitative trait loci influencing methamphetamine - and opioid - induced locomotor stimulation using B6.D2 congenic strains Camron Bryant, Dept of Human Genetics, University of Chicago, USA

During her residency in Human Genetics at the University of Bonn she pursued her research interest both in immunology and human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association studies.

Our first striking observation was that over one half of measured genes are affected by common genetic variation in human populations — called expression quantitative trait loci or eQTLs.

We have approaches in hand to search for expression quantitative trait loci (eQTLs) and splicing quantitative trait loci (sQTLs).

As a post doctoral fellow he shifted his interest to the use of genetic mouse modules to map quantitative trait loci involved in various hematopietic stem cell traits.

These regions can be clumped into larger areas of the genome called quantitative trait loci, which are known to contain genes that produce a specific physical effect, such as shaggy hair.

Engelhardt's group was responsible for mapping associations between genetic variants and gene expression levels on different chromosomes, a connection known as «trans - expression quantitative trait loci (trans - eQTLS).»

• Describe how protein quantitative trait loci (pQTLs) can provide insights into disease biology and improve the efficiency of drug development

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

Simulating the yield impacts of organ - level quantitative trait loci associated with drought response in maize: A «gene - to - phenotype» modeling approach.

They then used a genetic technique called quantitative trait locus analysis to search for the genes involved in generating phenolics in the most promising progeny.

The exciting aspect of submergence was that they could bring in what is known as a «quantitative trait locus» — a more genetically complex region that influences measurable changes to the crop.

Further, his group pioneered expression quantitative trait locus (eQTL) studies, which enabled variation in global gene expression to be applied to genetics of complex human diseases.

SM / J mice carry a number of rare polymorphic alleles and are often matched to other strains for quantitative trait locus analysis.

LG / J mice are often compared to SM / J (Stock No. 000687) for quantitative trait locus analysis in the areas of atherosclerosis, obesity, and mandible size.

SM / J mice carry a number of rare polymorphic alleles and are often matched to LG / J (Stock No. 000675), A / J (Stock No. 000646) or NZB / BINJ (Stock No. 000684) for quantitative trait locus analysis.

7) and have now localized the underlying quantitative - trait locus (QTL) in a comprehensive single - nucleotide polymorphism (SNP) map.

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP - 25, and 5HT1B

Not exact matches

«For anorexia nervosa, researchers implicate genetic locus on chromosome 12: Powerful genomic study of anorexia nervosa conducted to date to identify the common roots anorexia shares with psychiatric, metabolic traits.»

Adaptation in quantitative traits likely often occurs through subtle shifts in allele frequencies at many loci, a process called polygenic adaptation.

We demonstrate that, whereas the mean admixture under assortative mating is equivalent to that of a randomly mating population, the variance of admixture generally increases with higher levels of positive assortative mating and decreases with negative assortative mating, analogous to classic theory on assortative mating by single locus genotypes or traits.

Using genome - wide and custom genotyping arrays, a SciLifeLab - associated research group has found that loci associated with blood lipid levels are often associated with cardiovascular and metabolic traits, including coronary artery disease, type 2 diabetes, blood pressure, waist - hip ratio and body mass index.

In the last decade, genome - wide association studies (GWAS) enabled by cheap, high - throughput SNP genotyping have identified thousands of loci that influence disease susceptibility, quantitative traits, and other complex phenotypes.

CRGGH continues to use genomic data generated in African populations to refine and fine - map loci identified in European and Asian populations for multiple traits including glucose, uric acid, bilirubin, CRP and serum lipids.

As a result of their equally balanced admixed ancestry, the Malagasy may represent an ideal population in which to identify loci underlying complex traits of both anthropological and medical interest.

A genome - wide association study reveals loci influencing height and other conformation traits in horses

Genome - wide association study identifies two novel Loci with sex - specific effects for type 2 diabetes mellitus and glycemic traits in a korean population

The authors cross-referenced lncRNAs from FANTOM CAT with established GWAS loci, finding that 40.7 % of lncRNA genes were associated with at least one trait.

Even so, the authors found several significant associations, some near known loci for these traits, and others in potentially novel regions.

Many, if not most of the genomic loci associated with human traits lie in noncoding regions.

Recent genetic association studies identified variants in a locus on chromosome 15 (specifically, in the adjacent genes HERC2 and OCA2) that are major determinants of eye color, but the trait is influenced by interaction among at least ten different genes.

135/6: 00 Exome - wide study identifies loci displaying pleiotropic associations with multiple cardiometabolic traits in continental Africans.

The involvement of only one of Drosophila's four chromosomes suggests a simple genetic basis for the pheromone signature and may mean that the trait resides at a single genetic locus.

In recent years pleiotropy, the phenomenon of one genetic locus influencing several traits, has become a widely researched field in human genetics.

In the past few years, functional genomics, epigenomics, and regulatory genomics datasets have begun to drive the formulation and testing of mechanistic hypotheses that link specific genetic variants within implicated loci to human traits and phenotypes.

Genome - wide association studies (GWAS) have detected association between variants in or near the Lysophospholipase - like 1 (LYPLAL1) locus and metabolic traits, including central obesity, fatty liver and waist - hip ratio.

To date, a diverse set of genetic approaches have led to the discovery of over 97 loci influencing glycaemic traits.

Local selection on chromosomal inversions may play a role in this process, suggesting potential for spatiotemporal stability of the coastal hybrid form and providing resilience against introgression of medically - important loci and traits, found to be more prevalent in inland A. gambiae.

Located just below the E / e Locus on the known canine coat color genetic interaction flowchart, the K locus is important to understanding whether or not a dog will express agouti traits in its coat color or if it can pass on agouti expression to its offspLocus on the known canine coat color genetic interaction flowchart, the K locus is important to understanding whether or not a dog will express agouti traits in its coat color or if it can pass on agouti expression to its offsplocus is important to understanding whether or not a dog will express agouti traits in its coat color or if it can pass on agouti expression to its offspring.

One of the alleles at each locus is dominant and determines the traits, like coat color, portrayed in the dog.

The most basic genetic scenario is where a gene on a specific locus determines each trait.

This trait was formerly attributed to the Agouti (A) locus as AS, but recent breeding studies had shown this not to be the case.