Sentences with phrase «transcription factor networks»

Another research field is the understanding of gene regulatory principles on the level of small - scale transcription factor networks.

Distinct transcription factor networks predicate different tumor identities, corresponding to sympathetic noradrenergic or mesenchymal / neural - crest cell like identities.

Our work indicates that only a small fraction of the population resides at the top of the hierarchy, that lineage priming (co-expression of stem cell and lineage specific genes) characterizes pluripotent stem cell populations, and that extrinsic signaling pathways are upstream of transcription factor networks that control pluripotency.

Using computational methods, researchers applied that information to reconstruct the transcription factor networks responsible for medulloblastoma subtype diversity and identity, providing previously unknown insights into the regulatory landscape and transcriptional output of the different medulloblastoma subtypes.

Novel hybrid phenotype revealed in Small Cell Lung Cancer by a transcription factor network model that can explain tumor heterogeneity.

His interest lies in defining the transcription factor networks that control the self renewal and differentiation of embryonic and neural stem cells and their relation to human disease.

Towards resolving the transcription factor network controlling myelin gene expression.