Sentences with phrase «transcription factors essential»

Therefore, the question of what are the transcription factors essential for RIG - G gene induction remains open.

Found that muscle - specific histone methyltransferases and microRNAs regulate the activity of Hand2, a transcription factor essential for ventricle formation and more recently showed that microRNAs can efficiently guide stem cell fate decisions.

Not exact matches

Previous research had shown that Pax7 (a paired - box transcription factor) is essential to this regeneration.

«Our research has demonstrated unequivocally that the AP2 - G transcription - factor protein is essential for flipping the switch that initiates the transformation of malaria parasites in the blood from the asexual stage to the critical sexual stage of their life cycle,» Llinás said.

miRNA - 335, a messenger nucleic acid, regulates the endodermal transcription factors Sox17 and Foxa2 and is essential for the differentiation of cells within this germ layer and their demarcation from the adjacent mesoderm.

Furthermore, they found that a transcription factor group essential for blood vessel differentiation (ETS / GATA / SOX) has a previously unknown role.

While scientists have long known that a group of transcription factors are needed for stem cell maintenance, the sheer number of possible interactions among them has made the question of which are essential too complicated to address in the laboratory alone.

XPD encodes one of the two helicase components of basal transcription / DNA repair factor IIH (TFIIH), a ten - subunit, multifunctional complex that is essential for multiple processes, including basal transcription initiation and DNA damage repair via the nucleotide excision repair (NER) pathway [6,7].

Frank Mercurio and Anjana Rao report the cloning of the IκB kinases IKK - 1 and IKK - 2, the essential upstream regulators of the transcription factor NFκB.

A group of transcription factors collectively called the eye field transcription factors or EFTFs (pax6, rx1, tbx3 [or ET], nr2e1 [or tailless], six3, lhx2, and six6 [or optx2]-RRB- and the neural patterning gene otx2 are essential for normal eye formation [6].

Distinct and essential roles of transcription factors IRF - 3 and IRF - 7 in response to viruses for IFN - α / β gene induction.

Suppose you run a ChIP - seq experiment (think «GPS for proteins») for NANOG, an essential transcription factor in embryonic stem cells (ESCs).

T - box transcription factors T / Brachyury homolog A (Ta) and Tbx16 are essential for correct mesoderm development in zebrafish.

Transcription factor Nrf2 is essential for induction of NAD (P) H: quinone oxidoreductase 1, glutathione S - transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates.