Sentences with phrase «transcription of the key genes»

The susceptibility of German shepherds to chronic diarrhoea is not due to a failure of transcription of key genes encoding molecules involved in mucosal IgA secretion In collaboration with scientists at the University of Bristol, UK, WALTHAM investigated a potential cause of the susceptibility of German shepherd dogs to chronic diarrhoea (Peters et al. 2005).

Not exact matches

A key function of c - MYC is to regulate the transcription of numerous genes.

In addition, when these transcription factors lose their function, terminal differentiation into the vascular endothelium (completion of differentiation) is completely suppressed, and genes that are key to differentiation into vascular endothelial cells as well as transcription factors that maintain the undifferentiated state are adversely induced.

The researchers used this live - imaging technique to study fly embryos at a key stage in their development, approximately two hours after the onset of embryonic life where the genes undergo fast and furious transcription for about one hour.

Shimon Sakaguchi and colleagues report that the transcription factor Foxp3 is a key regulatory gene for the development of regulatory T cells.

FoxO1 Deacetylation Regulates Thyroid Hormone - induced Transcription of Key Hepatic Gluconeogenic Genes.

The STAT3, in turn, goes into the nucleus and it binds to a number of genes, and this is particularly happening in the hypothalamus and that we don't know all of the mechanisms, but this activation of the STAT3 transcription factor is key in exerting the leptin signal, and leptin action.

These experimental data establish the retromer complex as a key spatiotemporal regulator of IFNAR endosomal sorting and a new factor in type - I IFN - induced JAK / STAT signalling and gene transcription.

The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.

Nevertheless, sponges share key adhesion and signalling genes7, 8,9,10,11 with eumetazoans, as well as other genes important in body plan patterning such as developmental transcription factors12, 13,14,15; sponge embryos and larvae (Fig. 1) are readily comparable to those of other animals12, 16.

The 1500 transcription factors (TFs) within the human genome perform a key role in determining the set of active genes within a specific cell, as well as the magnitude of activity.