Sentences with phrase «transcriptional gene silencing»

TEV - B is a transgenic tobacco plant that expresses a mutated P1 / HC - Pro suppressor of Post Transcriptional Gene Silencing.

Younger ST, Corey DR. Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters.

By probing the three dimensional structure of this protein complex, called RNA - Induced Initiation of Transcriptional gene Silencing (RITS), scientists from Cold Spring Harbor Laboratory (CSHL) and their collaborators at St. Jude's Research Hospital have discovered new details of how its various parts or «domains» contribute to heterochromatin assembly and gene silencing.

In other work, the lab is exploring the mechanisms of heterochromatin formation and gene silencing through the study of a protein complex called RNA - induced initiation of transcriptional gene silencing (RITS).

A major effort in the lab is to elucidate the active components of this process and to apply transcriptional gene silencing in a therapeutic setting.

Not exact matches

Indeed using genome - wide transcriptional profiling, the researchers revealed that expression of clipped H3.3 silences genes that regulate the division and duplication of a cell.

We have found that blastocysts produced by suboptimal IVC exhibit transcriptional repression of some genes (Sox2, Hdac1, Kap1, Dnmt1, and Dnmt3a) that are modifiers of epigenetic gene silencing through the regulation of the transcription of specific genes, which involves changes in the chromatin state.

Although we could confirm a function of CHRAC / ACF in gene silencing, the extent of transcriptional repression scored in our tethering system was much stronger compared to the one in developing embryos.