Sentences with phrase «transcriptome analysis»
"Transcriptome analysis" refers to the study of all the messenger RNA (mRNA) molecules present in a cell or tissue at a specific time. It helps understand which genes are actively expressing and provides insights into the overall functioning of an organism or its response to different conditions. Full definition
In the new study, Kavitha T. Kuppusamy, the lead author in the article and senior fellow in Hannele Ruohola - Baker's lab, performed transcriptome analysis of RNA produced in 20 - day - old human embryonic stem cell - derived cardiomyocytes and in more mature, 13 - month - old versions of these cells This type of analysis details the types and levels of RNA produced in cells at a particular time.
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Panels B and C. mRNA expression analysis of genes involved in blood cholesterol regulation and fatty acid metabolism, as quantified by transcriptome analysis, was performed in enhanced hiPS - HEP cells from C12, C18, and C22 on Day 12 post-thawing (n = 2 batches per cell line) and compared to hphep cells on Day 1 post-thawing (n = 3 donors).
This was further supported by comparative transcriptome analysis in the noble scallop [14], in which gene scavenge receptor class B like - 3 was only expressed in the blood of orange scallops (i.e., not in brown ones).
This single cell transcriptome analysis followed by computational analyses enabled the team to identify the gene expression profiles of cells in the process of changing from ES cells to 2CLCs.
I am currently involved in RNA sequencing for two projects focused on transcriptome analysis of immune cells in various immunological diseases and cancer.
13/3: 00 Comprehensive transcriptome analysis using synthetic long read sequencing reveals molecular co-association and conservation of distant splicing events.
A large variety of methods is used including genetic, molecular and cytogenetic techniques, fluorescence in situ hybridisation and DNA «combing», as well as high throughput sequencing approaches such as DNA - seq for mutation landscape analyses, RNA - seq for transcriptome analyses and ChIP - seq mapping of chromatin - associated proteins and their genome - wide modulation in response to DNA damages.
Comprehensive transcriptome analyses reveal tomato plant responses to tobacco rattle virus - based gene silencing vectors
«St. Laurent Institute has adapted true single - molecule sequencing technology to global transcriptome analysis, providing state - of - the - art technology for the measurement of the output of the human genome,» said Georges St. Laurent III, Scientific Director of the St. Laurent Institute.
Further transcriptome analysis found multiple deregulated pathways, especially PRC2 / EZH2, in KDM6A - mutated urothelial bladder carcinoma.
According to Paek, «Genome - wide transcriptome analysis using drought - tolerant or - susceptible variants is a promising method to reach the goal of understanding drought tolerance».
Deep RNA - Seq data from the metastatic sample also permitted transcriptome analysis, though its presentation was brief.
Our dry - lab expertise is focused on sequence analysis, with special focus on next - generation sequencing transcriptome analyses.
van der Lee R, Szklarczyk R, Smeitink J, Smeets HJ, Huynen MA, Vogel R. Transcriptome analysis of complex I - deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system.
The project is supported by the Knut and Alice Wallenberg Foundation and includes proteome analysis based on more than 25 000 antibodies targeting more than 17 000 unique proteins, combined with transcriptome analysis covering all 20 000 human protein coding genes.
Research within the Center levarages cross-translational studies that seek to integrate and mine information generated by systems biology platforms such as transcriptome analysis by microarray technology, microRNA profiling, siRNA screens and global proteomic and metabolomic profiling.
They employed whole genome microarray analysis to perform sample - matched transcriptome analyses.
Labs have started tackling the problem with a tool called single - cell transcriptome analysis, which gives readouts of all the genes that are active in individual cells.
A Large - scale sequencing of genome, proteome, microbiome, and transcriptome analyses of colorectal cancer tissue has allowed researchers to better understand colorectal cancer subtypes.
Panel C. mRNA expression analysis on HNF4α and ASGPR1, as quantified by transcriptome analysis, was performed on enhanced hiPS - HEP cells from C12, C18, and C22 on Day 13 post-thawing (n = 2 batches per cell line), and on hphep cells on Day 1 post-thawing (n = 3 donors).
«Algorithm for reducing errors in transcriptome analysis.»
The results also show how the metabolic signposts of cancer cell growth and EMT can be predicted based on the transcriptome analysis of EGFR signaling genes alone (where current methods are inconsistent)-- thus supporting the idea of cell specific anti-cancer interventions.
The researchers also performed a transcriptome analysis comparing peripheral nerves with or without TAZ / YAP.
Panel C. mRNA expression analysis of ALB and α1AT, as quantified by transcriptome analysis, was performed in enhanced hiPS - HEP cells from C12, C18, and C22 on Day 13 post-thawing (n = 2 batches per cell line) and compared to hphep cells on Day 1 post-thawing (n = 3 donors).
Dorian Freudenreich (Brand, TUD)-- «Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells during neurogenesis and regeneration of the adult zebrafish telencephalon» (2010)
These new data suggest that transcriptome analysis can be used as a tool to predict the protein copy numbers per cell.
P0051: Transcriptome Analysis of Bemisia tabaci during Tomato yellow leaf curl virus (TYLCV) Acquisition and RNA Interference to Manage Whitefly - transmitted Viruses
Transcriptome analysis in the beet webworm, Spoladea recurvalis (Lepidoptera: Crambidae).
To identify specific pathways responsible for the observed biological effects, we performed a transcriptome analysis.
He leads the NIH - NCI - funded Cancer Genomics Laboratory at the Kimmel Cancer Center where he works on mRNA expression profiling for the retinoblastoma pathway, X-linked mental retardation, and transcriptome analysis of platelets in patients with heparin induced - thrombocytopenia.
The studies are a comprehensive analysis of disease - associated changes using a panel of state - of - the - art technologies including whole - transcriptome analysis (RNAseq), copy number variation (CNV) analysis and whole - exome sequencing (WES).
Overall, our transcriptome analyses indicated that, whereas the iPSCs are globally similar to hESCs, they are not indistinguishable, primarily due to the insufficient suppression or induction of NSC - specific or early embryonic - specific genes, respectively, as well as a class of genes that was upregulated during the reprogramming step.
What I really need to extract are coordinates of lowly informative regions, define them as intervals in Galaxy for example, and use them to screen out dodgy results from my transcriptome analysis.
Transcriptome analyses of seed development in grape hybrids reveals a possible mechanism influencing seed size