Whole genome and whole
transcriptome sequencing of 31 pediatric Asian patients with T - cell acute lymphoblastic leukemia found that about 10 percent had the same alteration in a non-coding region of DNA.
To annotate the genome, the team generated
transcriptome sequence data — which can be used to measure gene expression based on RNA levels — in 12 different tissues types.
Split Pool Ligation -
based Transcriptome sequencing (SPLiT - seq) is a scalable technique for characterizing RNA in individual cells that can be used to identify the various cell types found in the brain and other tissues.
For 18 species in the PLAZA data set, as well as A. trichopoda, P. sitchensis, P. abies, and translated P.
taeda transcriptome sequences, we further break down the protein - to - genome alignments that passed the initial cutoff into three categories: ESS ≥ 90, 90 < ESS ≤ 80 and 70 ≤ ESS < 80 (Figure 1).
With the X Ten and other instruments, we can provide custom - targeted, exome, whole genome, and / or
transcriptome sequencing for humans and model organisms.
Du X, Li L, Zhang S, Meng F, Zhang G. SNP Identification
by Transcriptome Sequencing and Candidate Gene - Based Association Analysis for Heat Tolerance in the Bay Scallop Argopecten irradians.
Our lab has a strong track record in integration of large - scale genome and
transcriptome sequencing data sets to characterize the genetic architecture of variants that affect the transcriptome.
The Ion Proton ™ System is the first benchtop non-imaging semiconductor sequencing system capable of human - targeted genome, exome, or
transcriptome sequencing in a few hours — with DNA - to - variants called in a single day.
Previous studies have published bay scallop expressed sequence tags [23, 24] and transcriptome sequences [17], which provided valuable resources for gene cloning.
Draft genome assembly (high coverage) and
transcriptome sequencing of 14 FBT genomes that infect various body sites
Draft genome assembly and
transcriptome sequencing of five Glossina genomes and two comparative genomes; low coverage genome sequencing of ~ 12 field populations.
Transcriptome sequencing and development of an expression microarray platform for the domestic ferret.
We are also interested in leveraging on
transcriptome sequencing to improve the interpretation of the personal genome.
In this study we have integrated genome and
transcriptome sequencing data to understand the landscape of functional variation in human populations.
Transcriptome sequencing is incredibly valuable for cancer genomics, because it offers insights into the immediate molecular effects of somatic mutations.
By leveraging the exponential improvements in the semiconductor industry (known as Moore's Law), the Ion Proton ™ Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to
transcriptome sequencing.
This is a landmark study not only due to the size, but the systematic characterization of each case using whole - genome sequencing (WGS), exome sequencing (WES), and
transcriptome sequencing (RNA - seq).
Integrated genome and
transcriptome sequencing of the same cell.
Ryan Morin, a graduate student in the Marra lab, walked us through a summary of
transcriptome sequencing and how it can be used not only for gene expression, but also discovery of mutations and characterization of alternate splicing.
Transcriptome sequencing and whole genome expression profiling of chrysanthemum under dehydration stress