Sentences with phrase «transduction of»

The idea of the transduction of memory into the physical of the body is often observed by practitioners of body work such as yoga.

For EBI2 transduction of BM - derived cells, BM cells were harvested 4 days after 5 - flurouracil (Sigma) injection and cultured in the presence of recombinant IL - 3, IL - 6, and mouse stem cell factor (SCF)(100 ng / ml; Peprotech; Rocky Hill, NJ).

The transduction of the genes into the primary cells requires the lentivirus and the transduction is much less efficient.

Transduction of the lentivirus into the mammary transplants was confirmed by the expression of ZsGreen.

This induced pluripotent stem cell (iPSC) line was generated from IMR90 fetal lung fibroblasts by viral transduction of a combination of OCT4, SOX2, NANOG, and LIN28 genes.

(A) Expression of pluripotency markers from iPSCs (HiPSC - 1 control) generated following retroviral transduction of unsorted HUF1 cells.

Introducing new DNA often is achieved by viral transduction of target cells with a therapeutic transgene, through either a direct or cell - based gene therapy modality.

The novel reprogramming approach employed the retroviral transduction of Oct4, Sox2, and Klf4 in mouse embryonic and adult fibroblasts followed by treatment with the GSK3β Inhibitor BIO and the pleiotropic cytokine Oncostatin M (OSM).

In this study, we established mouse iPS cell lines from NPCs of neonatal EGFP - transgenic mice on the HFF feeder cells via viral transduction of 4 factors, combined with application of 2i.

Manno, Catherine et al. «Successful Transduction of Liver in Hemophilia by AAV - Factor IX and Limitations Posed by the Host Immune Response.»

Kim Y - S, Wielgosz M, Hargrove P, Kepes S, Gray J, Persons D, Nienhuis A. Transduction of Human Primitive Repopulating Hematopoietic Cells with Lentiviral Vectors Pseudotyped with Various Envelope Proteins.

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.

She did her PhD on the transduction of the Notch signal in mammals in Alain Israël laboratory at the Pasteur Institute, Paris; she realised her postdoc with Iva Greenwald, at Columbia University NYC, on vulva organogenesis in C. elegans.

Transduction of the mammary epithelium with adenovirus vectors in vivo.

Sophie Jarriault did her PhD on the transduction of the Notch signal in mammals in Alain Israël laboratory at the Pasteur Institute, Paris.

Systemic FIV vector administration: transduction of CNS immune cells and Purkinje neurons.

Lipid and cationic polymer based transduction of botulinum holotoxin, or toxin protease alone, extends the target cell range and improves the efficiency of intoxication.

«Conventional techniques of producing transgenic animals, such as microinjection of genes into eggs and the retroviral transduction of genes into embryos, often produce many animals that are mosaic, which means they do not contain the foreign gene in all their cells.

We will consider the likelihood that viral transduction of this short peptide could attenuate Aβ production and deposition in AD mice, and rescue their memory function.

These cells were immortalized by retroviral transduction of the SV40 T antigen and Telomerase reverse transcriptase (TERT), the catalytic subunit of the telomerase complex [4], and then termed HMLE (Human Mammary with Large T and TERT).

OMC also aims at potentiating the existing Conditional Mutagenesis Facility by implementing novel approaches to attain tissue -, stage - and site - specific transgene expression in mouse mutant strains, mainly through lentiviral vector - mediated transduction of blastocysts.

This physical link between the cytoskeletons of neighboring cells allows for the generation and transduction of mechanical signals.

Surprisingly, the application of larval oral secretions inhibited the transduction of calcium signals to neighboring leaves in the experiment.

By functionally linking the signal transduction of melanopsin to the control circuit of the nuclear factor of activated T cells, we have designed a synthetic signaling cascade enabling light - inducible transgene expression in different cell lines grown in culture or bioreactors or implanted into mice.

Not exact matches

Blueberries also stimulate the growth of new nerve cells and facilitate better communication between nerve cells via a process known as transduction.

at The Scripps Research Institute and the Burnham Institute, and also at the National Institutes of Health, where her studies spanned signal transduction, cell migration, and neuronal development.

These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.

In addition to authoritative insights and collections of reviews, features, and News Focus articles in Science, Science's Signal Transduction Knowledge Environment and the Science of Aging Knowledge Environment will offer special content on drug discovery.

[See also this week's online Science of Aging Knowledge Environment (SAGE KE) and Signal Transduction Knowledge Environment (STKE)-RSB-.

«Dr. Smith, I'm soon going to be leaving the biochemistry program here at Purdue with a Ph.D. involving signal transduction, and I am wondering if you might make a recommendation of some contacts at your company whom I could talk with.

The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

It is expected that the molecular mechanisms underlying the inhibition of interferon signal transduction by C proteins would then be fully identified.

The H Foundation and a Signal Transduction in Cancer Training Program of the National Cancer Institute supported the research.

«The Cancer Genome Atlas is a really rich and growing database of publicly available data created to help us understand cancer,» said Horvath, who is a program co-leader of the Signal Transduction in Cancer program at the Lurie Cancer Center.

Peter Parker of the Imperial Cancer Research Fund in London says he is delighted that a drug targeting signal transduction is now in trials.

Mutations of the gene Lps selectively impede lipopolysaccharide (LPS) signal transduction in C3H / HeJ and C57BL / 10ScCr mice, rendering them resistant to endotoxin yet highly susceptible to Gram - negative infection.

At the end of the project, the transduction efficiency of the newly made retroviral vectors was tested in hematopoietic cells, and here my «old» techniques came in handy.

In 2014, Gu's research team overturned the common assumption that transduction from the mechanical force takes place at the endings of the sensory nerves in Merkel discs.

Heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors constitute the largest family of eukaryotic signal transduction proteins that communicate across the membrane.

Lorenz Adlung Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Baden - Württemberg, D - 69120, Germany.

FosB is a transcription factor in the brain which, together with other molecules, is involved in so - called signal transduction (transmission of stimuli to the cells), that is to say conveys genetic information between the cells and also determines whether certain genes are activated or not.

«Depression: Evidence of serotonin signal transduction disturbances.»

Epidermal growth factor receptor (EGFR) signal transduction plays a major role in growth, proliferation and differentiation of mammalian cells.

Recent studies such as ours, however, establish protein phosphatases as positive and essential regulators of signal transduction, with remarkable substrate specificity and coordinated activities.

The isoforms beta ARK - 2 and beta - arrestin - 2 are highly enriched in and localized to the dendritic knobs and cilia of the olfactory receptor neurons where the initial events of olfactory signal transduction occur.

During the early years of my PhD studies, I was very fascinated by the exciting discoveries in the field of signal transduction, in particular how receptor tyrosine kinases are activated to transmit their signals and how protein complexes are formed through defined protein folds (domains) interacting with specific cellular targets.

In 1995, I began graduate studies on signal transduction by growth factors and receptor tyrosine kinases in the laboratory of Graeme Guy at the Institute of Molecular and Cell Biology (IMCB) in Singapore, obtaining my PhD in 2000.

The «Transduction» is a dance performance which focuses on the nature of intramolecular interactions, bringing the dynamics and the flow into the picture.

This reflects the high sensitivity of the method, allowing to detect the signal transduction and propagation, where only minimal conformational (geometric) changes occur.

I studied the process called signal transduction - transmission of the activating mechanical signal from outside the cell, across the cellular membrane, to FAK inside the cell, leading to the activation of the kinase.