When the researchers
transferred gut microbes from the twins into mice predisposed to develop a disease similar to MS, they found that after 12 weeks, three times as many mice receiving bacteria from MS patients developed brain inflammation as those receiving microbes from healthy donors.
«But when
we transferred the gut microbes from healthy people, the mice didn't get nearly as sick,» Baranzini says.
Many of the metabolic changes in the mice prone both to obesity and diabetes could be duplicated by
transferring gut microbes from mice treated with antibiotics to mice lacking normal gut microbes.
Not exact matches
The scientists
transferred the twins»
gut bacteria to mice predisposed to develop a disease that mimics MS. Twelve weeks after the transplant, about 40 percent more mice with
gut microbes from a twin with MS developed brain inflammation compared with mice that got
gut microbes from a twin without disease.
The procedure of
transferring stool to a patient — technically called fecal microbiota transplantation — was first performed in the United States in 1958 to treat an intractable case of C. difficile colitis, a gastrointestinal condition caused when the balance of
microbes in the
gut — called the microbiome — is destabilized or destroyed.
But bacteria in the animals»
gut can also
transfer the resistance genes to
microbes harmful to humans.
Already, he knows that most IBD patients have a far smaller range of microbial species in their
guts, compared to healthy people Stool
transfers help restore that diversity and all the possibly beneficial chemical compounds that those
microbes release into our bodies.
Research shows a way to
transfer a mom's
microbes to cesarean babies using probiotics from the birth canal, improving
gut bacteria and immune health.