Sentences with phrase «translational cancer studies»

The Foundation's scientific objectives are: Broadening our understanding of the links between human and companion animal cancer, creating a cross institutional collaborative platform, developing new approaches to research, and funding translational cancer studies that benefit both pets and people.

About The Puppy Up Foundation (herein referred to as «The Foundation») was established to fund comparative and translational cancer studies that can potentially benefit both pets and people as well as invest in national education and awareness initiatives about the epidemic of cancer in companion animals.

The Puppy Up Foundation's scientific objectives are: Broadening our understanding of the links between human and companion animal cancer, creating a cross institutional collaborative platform, developing new approaches to research, and funding translational cancer studies that benefit both pets and people.

Not exact matches

«Nonetheless, the proof of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

Their study published last week in Science Translational Medicine demonstrated that the fasting - mimicking diet reduced risks for cancer, diabetes, heart disease and other age - related diseases in human study participants who followed the special diet for five days each month in a three - month span.

The study was supported in part by the National Institutes of Health (DA024806, R01DA032889 - 01A1, DA018197 - 05); the Tufts Medical Center's Natalie Zucker and Susan Saltonstall grant; the Joel Alpert Foundation Grant; MD Anderson's Cancer Center Support Grant (DA026120); the National Center for Advancing Translational Sciences (UL1 TR000073); and the Toomin Family Fund.

The finding warrants research into adding drugs that could prevent the cancer from hijacking patients» repressive gene regulatory machinery, which might allow the original therapy to work long enough to eradicate the tumor, the researchers report in their National Institutes of Health - funded study, published in the current issue of Science Translational Medicine.

The results of the study were published this week in the journal Nature Medicine from researchers at Penn's Abramson Cancer Center, including senior author Carl H. June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the ACC, the University of Maryland School of Medicine, and Adaptimmune Therapeutics plc (Adaptimmune).

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

«Often it is impossible to visually distinguish cancer from normal brain, so invasive brain cancer cells frequently remain after surgery, leading to cancer recurrence and a worse prognosis,» says Dr. Kevin Petrecca, Chief of Neurosurgery and brain cancer researcher at The Neuro, and co-senior author of the study published today in Science Translational Medicine.

The Translational Genomics Research Institute (TGen) has uncovered possible genetic origins of breast cancer that spreads to the brain, according to a first - of - its - kind study published in the scientific journal PLOS ONE.

The study, published in the journal Science Translational Medicine, is an important step towards use of «liquid biopsies» to revolutionise breast cancer care — by changing the way cancer is monitored in the clinic and informing treatment decisions.

This advance in breast cancer research reflects the mission of Stem Cell Reports to provide an open - access forum that communicates basic discoveries in stem cell research as well as translational and clinical studies.

The study is published in the October 2016 issue of Translational Cancer Research.

In a study appearing in Science Translational Medicine, the researchers report they have effectively and safely employed this stem cell - targeting system in mice to treat metastatic breast cancer that had spread to the lung.

«This is a very exciting and interesting and, to be honest, important observation in the world of cancer susceptibility,» says Stephen Chanock, the chief of translational genomics at the National Cancer Institute in Bethesda, Maryland, who was not involved in the cancer susceptibility,» says Stephen Chanock, the chief of translational genomics at the National Cancer Institute in Bethesda, Maryland, who was not involved in the Cancer Institute in Bethesda, Maryland, who was not involved in the study.

The Medical Center includes the School of Medicine and the School of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of HCancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of Hcancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of HCancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of Health.

The Clinical Accelerator, building on 60 + years of CRI's dedication to funding the most innovative basic science in tumor immunology, enables experts to advance their most ambitious clinical and translational research ideas to cure cancer, and accelerates studies that one group or company could not do alone.

SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced the publication of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andCancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andcancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andcancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.

Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population atCancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population atcancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.

Two main examples of these translational studies we participated on can be exposed: The first Cog - Age clinical study (Pr F. Joly, Baclesse Caen) showed that cognitive decline can be detected 6 months after chemotherapy in breast cancer elderly patients.

The study, «Melanoma - intrinsic β - catenin signalling prevents anti-tumour immunity,» was funded by a Team Science Award from the Melanoma Research Alliance and a Translational Research Grant from the Cancer Research Institute.

The study, by O'Donnell; head and neck cancer specialists Everett E. Vokes, MD, physician - in - chief and chair of the Department of Medicine, and Ezra Cohen, MD; and several investigators from the CPT team and Department of Human Genetics, was published in the May 2011 Translational Research.

A chemotherapy drug used to treat brain cancer may increase vulnerability to depression by stopping new brain cells from growing, according to a new King's College London study out today in Translational Psychiatry.

The Divisions of Cancer Prevention (DCP) and Cancer Biology (DCB) at the National Institutes of Health (NIH) has awarded a $ 6 million grant to investigators at the University of Michigan to continue support for a Research Center in the Barrett's Esophagus Translational Research Network (BETRNet)-- this consortium studies the connection between Barrett's esophagus and risk for developing esophageal cCancer Prevention (DCP) and Cancer Biology (DCB) at the National Institutes of Health (NIH) has awarded a $ 6 million grant to investigators at the University of Michigan to continue support for a Research Center in the Barrett's Esophagus Translational Research Network (BETRNet)-- this consortium studies the connection between Barrett's esophagus and risk for developing esophageal cCancer Biology (DCB) at the National Institutes of Health (NIH) has awarded a $ 6 million grant to investigators at the University of Michigan to continue support for a Research Center in the Barrett's Esophagus Translational Research Network (BETRNet)-- this consortium studies the connection between Barrett's esophagus and risk for developing esophageal cancercancer.

Clairice Lloyd, CRA, is responsible for Medical Center program project proposals and awards, including the Cancer Center Support Grant (CCSG), Georgetown - Howard Universities Center for Clinical and Translational Science (GHUCCTS), Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening, and the Women's Interagency HIV Study (WIHS), as well as the Neurology Basic Science Department.

The following institutions contributed to the study: Technical University of Munich (Central Institute of Translational Cancer Research, Clinic and Policlinic for Internal Medicine II, Institute of Pathology), DKTK and DKZF Heidelberg; The Wellcome Trust Sanger Institute, Cambridge; Ludwig - Maximilians Universität (Anthropology & Human Genomics und Innere Medizin II des Klinikums Großhadern), Helmholtz Zentrum München (Research Unit Radiation Cytogenetics); Universidad de Oviedo (Bioquímica y Biología Molecular, IUOPA und CINN - CSIC), Instituto de Medicina Oncológica y Molecular de Asturias (IMOMA), Oviedo, University of Cambridge (Department of Veterinary Medicine), Instituto de Medicina Oncológica y Molecular de Asturias, Instituto de Biomedicina y Biotecnología de Cantabria.

A study published in Science Translational Medicine shows that small molecules that specifically inhibit an important selenium - containing enzyme may be useful in combating cancer.

Specific translational studies include: Molecular mechanisms of migration contribute to metastasis and subsequently thought to be central to the cancer progression poor clinical outcome for cancer patients.

The ECOG - ACRIN Cancer Research Group has developed multiple strong translational science resources that are fully integrated with the three scientific programs: Cancer Control and Outcomes, Therapeutic Studies, and Biomarker Sciences.

With ongoing studies in cancer care quality, outcomes prediction, clinical epidemiology, and medical decision making, we have a comprehensive portfolio of practice - and policy - relevant translational population sciences research in urologic cancers, building on the exceptional strengths of UNC Lineberger.

Funding provided by the Cancer Center Support Grant (CCSG) supports several types of pilot projects (1) highly innovative pilot projects focusing on proof - of - concept or translational research; (2) preliminary collaborative investigations that lead to multi-investigator grant awards or clinical trial; (3) projects that closely align with the Cancer Center's strategic plan and enhance key initiatives; and (4) pilot funding for junior investigators to jump - start independent projects or for more senior investigators looking to study a novel idea derived from discovery.

Alexandra Snyder, MD, is a translational physician scientist at Memorial Sloan Kettering Cancer Center (MSKCC) who specializes in the study of tumor genetics and response to checkpoint blockade immunotherapy in solid tumors, with a particular focus on ovarian cCancer Center (MSKCC) who specializes in the study of tumor genetics and response to checkpoint blockade immunotherapy in solid tumors, with a particular focus on ovarian cancercancer.

Cancer cells discharge these mutated proteins — which become markers for the immune system — as a result of genetic mutations, said study co-author Jonathan Serody, MD, UNC Lineberger's associate director for translational research.

Oncology investigators in the NC State Center for Comparative Medicine and Translational Research, for example, focus on understanding the pathogenesis and treatment of cancer through studies involving, in part, spontaneous models of cancer provided by Terry Center oncology patients.

«Our canine companions are not only man's best friend, but our study shows that dogs also can help human patients pursue battles against various types of cancer,» says Jeffrey Trent, Translational Genomics Research Institute president and research director and the study's senior author, in a release about the study.

Maybe I missed something or misread «The Translational Genomics Research Institute (TGen) and the Van Andel Research Institute (VARI) have created the Canine Hereditary Cancer Consortium, a program designed to study naturally occurring cancers in dogs to better understand why both pets and people get sick.»