Translational studies refer to research that focuses on turning the discoveries made in the laboratory (such as in experiments with cells or animals) into practical solutions that can improve human health or benefit society.
Full definition
«This unique relationship provides a rich environment for
translational studies in neurorehabilitation based on what we now know about the remarkable plasticity of the human central nervous system.
Our research has leveraged these models
for translational studies on human hematopoiesis, immunity, autoimmunity, infectious diseases, diabetes, regenerative medicine and cancer.
He did his postdoctoral training at the Karolinska Institutet in Stockholm, where he worked
on translational studies of cardiovascular genetics, combining wet - lab research with large, population - based studies.
Its biospecimen repository is still used in
translational studies of HTLV biology and pathogenesis by our lab and international collaborators.
I continue this line of research as such, and I currently am the principal investigator on multiple projects involving
translational studies involving cell or gene therapy -.
We couple fundamental biological research with
early translational studies to find new, innovative therapies that restore hope to cancer patients and their families.
Our faculty, trainees, and staff work in a number of preclinical laboratory models, integrate their work
into translational studies, develop new agents in collaboration with other St. Jude faculty, and use state - of - the - art clinical approaches to establish new knowledge and improve patient care.
In 2007, he was awarded a prestigious National Career Development Fellowship to
undertake translational studies in the epigenetic regulation of the immune cell signaling molecules in human asthma at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 2009.
Dr. Kaufman's Translational Imaging Laboratory, founded in 2004, executes preclinical, clinical, and
translational studies using innovative neuroimaging techniques to investigate the structure, function, and metabolism of the brain.
«Low level vitamin D during remission contributes to relapse in ulcerative colitis patients:
Translational study suggests higher vitamin D level may benefit ulcerative colitis patients.»
We are making a significant contribution to the advancement of knowledge on the pathogenesis of Cystic Fibrosis, in addition to
improving translational studies in the field of pulmonary infections.
Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence,
most translational studies relevant to the hematologic system are conducted in live animals.
Specific translational studies include: Molecular mechanisms of migration contribute to metastasis and subsequently thought to be central to the cancer progression poor clinical outcome for cancer patients.
This proposal represents a
novel translational study that targets a potential underlying pathogenesis of canine mitral valve disease.
The Wake Forest Institute of Regenerative Medicine (WFIRM) has a unique infrastructure that provides facilities and expertise
for translational studies, from basic preclinical findings all the way through Phase 2 clinical trials.
The second laboratory continues to focus attention on transplantation immunobiology in mouse models and
translational studies of human immunology in transplant recipients.
In 2007, he was awarded a prestigious National Career Development Fellowship to
undertake translational studies in the epigenetic regulation of the immune cell signaling molecules in human asthma under the mentorship of K. Mark Ansel, Ph.D., at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 2009.
«Understanding the mechanism of action of this peptide will help in
translational studies to further assess the potential for this peptide to be used in medicine,» Beales says.
«This work will fuel many functional and
translational studies and allow for new drug design venues.»
Several recommendations and important considerations emerged from
our translational study.
To inform the scientific community of pain research interests of NIH and to stimulate and foster a wide range of basic, clinical, and
translational studies on pain.
Two main examples of
these translational studies we participated on can be exposed: The first Cog - Age clinical study (Pr F. Joly, Baclesse Caen) showed that cognitive decline can be detected 6 months after chemotherapy in breast cancer elderly patients.
The analysis included only papers that reported new results from basic research experiments,
translational studies, clinical trials, metanalyses, and studies of disease outcomes.
Neil P. Shah, MD, PhD University of California, San Francisco San Francisco, CA Breakout Rotation 2: Research Teams in
Translational Studies (including optimizing partners in the lab)
Also, genes that code for receptor tyrosine kinases, a family of receptors on the surface of cells, may rearrange to form multiple distinct gene fusion partners, as evidenced in an article by Kulkarni, et al, on
a translational study involving a patient who developed a BRAF fusion following treatment with a BRAF inhibitor1.
The Stone lab leads a range of multicenter clinical and
translational studies in these areas.
With recent advances, single - cell analysis has become ripe for
translational studies.
NCCIH pain research spans basic, mechanistic, and
translational studies and clinical trials.