Sentences with phrase «translational studies using»

Not exact matches

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

«Understanding the mechanism of action of this peptide will help in translational studies to further assess the potential for this peptide to be used in medicine,» Beales says.

The study results, published in Science Translational Medicine, raise questions about the possible transmissibility of prion diseases via medical procedures involving skin, and whether skin samples might be used to detect prion disease.

The journal's home page explains that translational medicine «builds on basic research advances — studies of biological processes using cell cultures, for example, or animal models — and uses them to develop new therapies or medical procedures.»

Reporting the results of a second study from the same group, Dr Suzanne Drury, a translational research and development scientist from Great Ormond Street Hospital, will describe the team's experience in the use of NIPD (non-invasive prenatal diagnosis) to diagnose the disorder congenital adrenal hyperplasia (CAH).

The study, published in the journal Science Translational Medicine, is an important step towards use of «liquid biopsies» to revolutionise breast cancer care — by changing the way cancer is monitored in the clinic and informing treatment decisions.

«This study shows how translational research using basic science techniques in animal models can elucidate the underlying basis of human emotions and reasons for mental disorders, thereby pointing the way for treatment development,» says Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUIMC.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced the publication of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.

These models are used for both basic and translational research, including studies to investigate the role of tumor initiating cells in tumor relapse, tumor metastasis and therapy resistance.

A chemotherapy drug used to treat brain cancer may increase vulnerability to depression by stopping new brain cells from growing, according to a new King's College London study out today in Translational Psychiatry.

A new study published in the journal Science Translational Medicine reveals new steps in the development of diabetic retinopathy and shows that they can be prevented using targeted drugs.

In a study published Wednesday in the journal Science Translational Medicine, Chinese researchers detail a process by which a dedicated smartphone app is used to «switch on» engineered insulin - producing cells in mice.

Its biospecimen repository is still used in translational studies of HTLV biology and pathogenesis by our lab and international collaborators.

REVEAL IV is the first translational genetics study to focus upon the situation where mild early symptoms of a disease (phenotype) and known genetic risk marker (genotype) information can be used together to produce more imminent risk projections.

A 2017 study co-authored by John Bischof, professor of mechanical engineering at the University of Minnesota, and published in Science Translational Medicine, used specially coated iron oxide nanoparticles.

Group research aims to study the relations between nutraceuticals, physical activity, intracellular mechanisms, gene expression and microbiota using a translational approach to characterize the impact in the whole body of metabolic interactions studied in individual organs and tissues (in vitro / ex vivo: skeletal muscle, heart, bone, liver and kidney).

«Studies using optogenetics have the capacity to make an enormous impact on translational research,» she says.

Scientists have used the powerful gene editing tool CRISPR to reverse sickle cell disease in mice, according to a study published Wednesday in the journal Science Translational Medicine.

In a second study, published in the journal Stem Cells Translational Medicine, the team showed that in rodents they could use the same type of lung cell to successfully treat a model of IPF — a chronic, irreversible, and ultimately fatal disease characterized by a progressive decline in lung function.

Humanized mouse models, where human tumor tissue is engrafted into immunodeficient NOD SCID gamma (NSG) mice, are frequently used in oncology and infectious disease studies to provide valuable translational insights.