Sentences with phrase «translational studies with»

To extend novel observations generated from epidemiology studies to translational studies with direct clinical relevance.

Cell Host & Microbe will publish novel findings related to microbes (which includes bacteria, fungi, parasites, and viruses) from molecular and cellular biology to translational studies with particular emphasis on the interface between the microbe and its host (vertebrate, invertebrate, or plant; unicellular or multicellular).

Not exact matches

A study published in Translational Psychiatry earlier this year found regular yoga and meditation could help people with depression, especially if they meditated in conjunction with a workout.

«Nonetheless, the proof of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

A resurgence in whooping cough cases in the U.S. is likely due to incomplete vaccine coverage in the past combined with waning protection from the vaccine, according to a new study published in the March 28 issue of Science Translational Medicine.

«I think it's a very well - done study,» says Keith Vossel, a translational neuroscientist at the University of California, San Francisco (UCSF), who was not involved with the work.

The latest study of a new at - home test kit, published today in Science Translational Medicine, found that even untrained users were able to measure sperm count and concentration as well as motility (the percentage of actively moving sperm), detecting abnormal semen with 97 percent accuracy compared with traditional lab testing.

Dennis Miller, associate professor in the Department of Psychological Sciences in the College of Arts & Science and an investigator with the Bond Life Sciences Center, and researchers in the Center for Translational Neuroscience at MU, study therapies for drug addiction and neurodegenerative disorders.

With the technology on track for commercialization, Rogers» team, including Dr. Roozbeh Ghaffari, the director of translational science at CBIE, is continuing to test the microfluidic devices in scaled studies with an expanding collection of partnWith the technology on track for commercialization, Rogers» team, including Dr. Roozbeh Ghaffari, the director of translational science at CBIE, is continuing to test the microfluidic devices in scaled studies with an expanding collection of partnwith an expanding collection of partners.

The study, which was published in the last issue of Science Translational Medicine, reports early plasma cytokine signatures that correlate with, and predict, the immunogenicity and reactogenicity of the vaccine.

As a clinician - scientist with a translational research focus, Dr. Deininger is heading an extramurally funded research laboratory that is dedicated to the study of signaling pathways, drug resistance, and new molecular therapies in leukemia.

University of Alabama at Birmingham researchers have found that amounts of this microRNA are significantly elevated in the brains of experimental rats with induced depression from corticosterone treatment, in the post-death brains of humans diagnosed with MDD and in peripheral blood serum from living patients with MDD, according to a study by led by Yogesh Dwivedi, Ph.D., the Elesabeth Ridgely Shook Endowed Professor and director of Translational Research, UAB Mood Disorders Program, Department of Psychiatry.

«We've known for several years that people working directly with livestock are at increased risk for MRSA infections, but this is one of the first studies providing compelling evidence that everyday consumers are also potentially at risk,» says Lance Price, PhD, Director of the Antibiotic Resistance Action Center, which is based at Milken Institute SPH, and Director of Translational Genomics Research Institute Center for Food Microbiology and Environmental Health.

Researchers led by Lance Price, from the Translational Genomics Research Institute, USA, and Rupert Kaul, from the University of Toronto, Canada, studied the relationship of semen bacteria with HIV infection by analyzing semen samples from 49 men who have sex with men (MSM).

She ultimately chose to study leukemia patients» immune responses to bone marrow transplants, an area conducive to translational research in part because the work involves treating patients with human cells, which can be prepared at academic health centers.

A study coming out in Science Translational Medicine and led by University of Pennsylvania School of Veterinary Medicine researchers has shown that cats with NPC — which mirrors the human version of the disease — show vast improvements when treated with a compound called cyclodextrin.

Study enrollment of patients with and without lupus was supported by ResearchMatch, a service provided through the support of the Ohio State University Center for Clinical and Translational Science.

The three - year study conducted by McLean researchers points to specific neuroanatomical changes in human subjects with these illnesses, and specifically to neurons that regulate anxiety and stress response, according to Harry Pantazopoulos, PhD, assistant neuroscientist at McLean's Translational Neuroscience Laboratory and instructor in psychiatry at Harvard Medical School.

The study results, published in the journal Science Translational Medicine, suggest the thicker thread is associated with a three-fold increase in rate of baby death in the womb when compared to the thinner thread, and is associated with an increased rate of premature birth.

«We hope our findings reassure women with epilepsy and clinicians who are counseling these women on family planning,» says Jacqueline French, MD, professor of Neurology and Director of Translational Research and Clinical Trials at NYU Langone's Comprehensive Epilepsy Center, and the study's first author and co-principal investigator.

If the two methods independently come up with genes that are interconnected, «it would be a much more powerful way of prioritizing» what to study next, says computational biologist Michael Bittner of the Translational Genomics Research Institute in Phoenix, Arizona.

The pioneering study, conducted by researchers from the world - leading Sheffield Institute of Translational Neuroscience (SITraN), found that the C9orf72 protein, which is encoded by the C9ORF72 gene, functions in the autophagy pathway — something which is defective in patients with the most common inherited form of ALS and FTD.

Learn how to deal with all aspects of translational research, from study design to managing a lab.

We also conduct electrophysiological, biochemical, imaging, antd behavioral studies with various knockout and transgenic mice to determine how precise genetic manipulations that either activate or abolish specific translational control mechanisms alter synaptic function and behavior.

«The problem arises from autoimmunity, a condition that people with type 1 diabetes already have,» says Myra A. Lipes, M.D, investigator in the Section on Immunology at Joslin and principal investigator of a study published in the June 13 edition of the journal Science Translational Medicine.

This study reveals a new function for Hfq in ribosome biogenesis with implications for translational control.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

Finally, once all these studies satisfactorily, the teams I - Stem associate with appropriate clinical research teams to carry out the experimental protocols to transfer patient in the context of research called» translational «culminating in the clinical trials.

SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced the publication of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.

Individuals with psychopathic traits are highly skilled at learning to lie when measured against others who do not exhibit psychopathic tendencies, according to a new study published in the journal Translational Psychiatry.

Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.

An international peer - reviewed journal, it publishes open access basic research with a translational focus, as well as clinical trials, research into drug discovery and development, and epidemiologic studies.

He admits that this will take many years of basic biology research along with more translational studies into tissue engineering.

With the ability to integrate these data sets in a tightly linked, highly annotated manner, Labmatrix has the kind of flexibility, security and data access control today's scientists require for information management of biomarker discovery, next generation biobanking, pre-clinical and clinical studies and translational research efforts.

Furthermore, we have developed multiple collaborations with numerous other laboratories both within BCM, as well as outside of the institution to further enhance our studies both from a basic science and translational / clinical approach.

The ECOG - ACRIN Cancer Research Group has developed multiple strong translational science resources that are fully integrated with the three scientific programs: Cancer Control and Outcomes, Therapeutic Studies, and Biomarker Sciences.

Also, genes that code for receptor tyrosine kinases, a family of receptors on the surface of cells, may rearrange to form multiple distinct gene fusion partners, as evidenced in an article by Kulkarni, et al, on a translational study involving a patient who developed a BRAF fusion following treatment with a BRAF inhibitor1.

The expertise displayed by the teams and the platforms of the Department of Translational Research allows the support for maturation of translational research projects (proof of concept in vivo, target / biomarker identification and validation, ancillary biological studies coupled to clinical trials,...) of the Institut Curie alone or in collaboration with other academic teams or industrTranslational Research allows the support for maturation of translational research projects (proof of concept in vivo, target / biomarker identification and validation, ancillary biological studies coupled to clinical trials,...) of the Institut Curie alone or in collaboration with other academic teams or industrtranslational research projects (proof of concept in vivo, target / biomarker identification and validation, ancillary biological studies coupled to clinical trials,...) of the Institut Curie alone or in collaboration with other academic teams or industrial partners.

With ongoing studies in cancer care quality, outcomes prediction, clinical epidemiology, and medical decision making, we have a comprehensive portfolio of practice - and policy - relevant translational population sciences research in urologic cancers, building on the exceptional strengths of UNC Lineberger.

Your study teams are empowered with up - to - date, accurate and actionable insights on biospecimen and related patient informed consent activities, boosting trial execution productivity while reducing operational and compliance risks for both ongoing trials and future translational medicine studies.

This study addresses the requirements of each of the four CPEBs for mitotic phase transitions, with a particular focus on cytoplasmic polyadenylation and translational regulation.

Funding provided by the Cancer Center Support Grant (CCSG) supports several types of pilot projects (1) highly innovative pilot projects focusing on proof - of - concept or translational research; (2) preliminary collaborative investigations that lead to multi-investigator grant awards or clinical trial; (3) projects that closely align with the Cancer Center's strategic plan and enhance key initiatives; and (4) pilot funding for junior investigators to jump - start independent projects or for more senior investigators looking to study a novel idea derived from discovery.

Alexandra Snyder, MD, is a translational physician scientist at Memorial Sloan Kettering Cancer Center (MSKCC) who specializes in the study of tumor genetics and response to checkpoint blockade immunotherapy in solid tumors, with a particular focus on ovarian cancer.

The RegMed Track links basic molecular and cellular research with translational and clinical studies, and includes stem cell biology, molecular medicine, regenerative biology and translational research.

Can this new STEM CELLS Translational Medicine study provide improved burn injury wound healing with the help of ASCs?

In one recent study published in the journal Science Translational Medicine, scientists looked at people with recurring migraine headaches over the course of multiple attacks and found that when docs told patients they had high expectations that a treatment would work well, it did — even if it was a sugar pill, and even when the patients were told they were getting the placebo.

The 2015 study was part of ACER's Translational Research project, which is aimed at connecting researchers with practitioners, disseminating findings and translating them into evidence - based practice.

In the study, lead author Duncan Lascelles, CVM professor of small animal surgery and pain management, outlines an comprehensive argument for the translational power of utilizing companion animals with naturally occurring diseases as models of human conditions.

The VCS department, along with the Veterinary Teaching Hospital, has state of the art facilities, equipment and infrastructure for studying the health and diseases of animals, conducting clinical trials and translational research.