Not exact matches
Researchers used stem
cells to create retinal
pigment epithelium
cells, which were
transplanted into a patient's retina (left) in an area depicted by the black circle.
In people with severe eye disease,
transplants made from embryonic stem
cells (in region of black dotted circle) appear safe, and became larger and more
pigmented over time (right).
For example, there have been cases of
transplanting retinal
pigment epithelium and spine
cells from stem
cells.
To test their idea for the dry form, Amir Kashani of the University of Southern California in Los Angeles and his colleagues coated 6 by 4 - millimetre slithers of polymer with retinal
pigment epithelial
cells they had grown, then
transplanted these into four people.
In contrast, EFTF - expressing pluripotent
cells formed YFP - expressing,
pigmented spheroids in 23 % of
transplants (N = 566).
In this pilot case, a sheet of retinal
pigment epithelial
cells was
transplanted into a patient.
The large
pigmented CD68 - positive
cells observed in the subretinal space at 13 weeks are likely to be macrophages / microglia filled with melanin [46], [47] from the
transplanted human iPS - RPE
cells.