Sentences with phrase «transplantation tolerance»

During her early career, Dr. Gregori made pioneer work in studying the role of vitamin D3 and its analogues in transplantation tolerance and in preventing autoimmune diabetes, working in the group of Prof. L. Adorini.

«Transplantation tolerance appears to be a resilient and persistent state, even though it can be transiently overcome,» said Anita Chong, PhD, professor of transplantation surgery at the University of Chicago and co-senior author of the study.

«The methods for achieving transplantation tolerance differ between mice and humans, but the mechanisms that maintain it are likely shared,» said Marisa Alegre, MD, PhD, professor of medicine at the University of Chicago and co-senior author on the study.

Made major contributions to the field of immunology through his studies on immune tolerance in animal models, with particular focus on transplantation tolerance and autoimmunity, in addition to pioneering the use of therapeutic monoclonal antibodies against T cells, resulting in the development of Campath - 1H, the first humanised monoclonal antibody to be used therapeutically.

Citation: Bonde S, Chan K - M, Zavazava N (2008) ES - Cell Derived Hematopoietic Cells Induce Transplantation Tolerance.

ES cells provide new opportunities for developing and establishing new treatments, including transplantation tolerance induction, because of their unique characteristics: lack of MHC antigens, poor expression of co-stimulatory molecules and lack of T cells that can trigger graft - versus - host reaction.

Here, we sought to study whether ectopically expressed HOXB4 allows the differentiation of ES cells into HPCs that can be utilized to confer transplantation tolerance.

Pivotal role of the B7: CD28 pathway in transplantation tolerance and tumor immunity.

Bone marrow cells induce stable mixed chimerism under appropriate conditioning of the host, mediating the induction of transplantation tolerance.

Five decades ago Medawar and colleagues published an article in Nature [1] demonstrating that transplantation tolerance can be acquired; in these studies tolerance was strongly associated with donor leukocyte chimerism [1], [2].