«Our major CIRM - funded programs, aimed at engineering young stem cell - derived astrocytes to secrete GDNF, then
transplanting those cells back into patients, take on even greater importance, given this aging phenomenon,» said Svendsen, the Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine.
Not exact matches
Da Cruz and his team grew replacement RPE
cells from human embryonic stem
cells on a thin plastic scaffold, before
transplanting the tissue into the
back of each volunteer's eye.
Jacob's team has
transplanted the
back - up or «alternative» respiratory machinery from the mitochondria of lower organisms to human
cells, showing that it can protect against pathological stresses, and even lethal poisons like cyanide, that target the mitochondria.
However, to be truly useful, one must be able to
transplant the bacterial chromosome from yeast
back into a recipient bacterial
cell.
Rashid's ultimate hope is that one day scientsts will be able to correct the diseased
cells in the lab and
transplant them
back into the patient, but he cautions that
cell - based therapies won't be available anytime soon.
The
cells were derived from eggs that had been injected with DNA from the patients, so they could eventually be
transplanted back to replace or correct the patient's diseased
cells without fear of immune rejection.
After fishing stem
cells from each individual's own blood, the researchers inserted a normal version of the ABCD1 gene into some of the
cells and
transplanted them
back into the kids.
Researchers can create iPSCs from a patient's blood or skin
cells, and use these patient - specific
cells to study diseases or even create new tissues that could be
transplanted back into the patient as therapy.
Researchers already envision
transplanting ready - made embryonic stem
cells back into people, providing cures for a huge range of diseases, from diabetes to paralysis to Alzheimer's.
This process multiplies the original SSCs by 18,000-fold so there are enough
cells to
transplant back into the patient when he reaches adulthood.
Scientists aim to freeze a sample of the boys» testicular tissue so that when they reach adulthood, spermatogonial stem
cells (SSCs) found in the tissue can be reproduced and
transplanted back into the patients.
The experiment Orwig has in mind is to use gene - editing technology to fix this flaw in the sperm - forming stem
cells and then
transplant them
back into infertile mice, thereby demonstrating a potential treatment for male infertility.
The patch of hair on this bald mouse's
back is the result of a single
transplanted stem
cell.
The anti-sickling HSC will be
transplanted back into the patient's bone marrow and multiply the corrected
cells that make red blood
cells without sickling.
This feature would be critical for clinical uses, such as
transplanting stem
cells — with their defects corrected —
back into patients, but the researchers emphasize that years of further study remain before such treatments might be possible.
To treat hereditary blood diseases, doctors could take a sample of bone marrow
cells from a patient, correct the faulty gene, and then grow healthy
cells in the bioreactor and
transplant them
back into the patient.
«The patients who participated in these trials had relapsed as many as four times, including 60 percent whose cancers came
back even after stem
cell transplants.
But to complete their maturation into sperm, which have half the number of chromosomes of nongerm
cells, these PGC - like
cells were
transplanted back into mouse testes.
ONJ staff gave Suzi the confidence to begin treatment, a stem
cell procedure where her own
cells were treated and stored, ready to be
transplanted back at a later date.
Patients receive one of two types of stem
cell - based
transplants: autologous, in which a patient donates and receives
back his / her own stem
cells; or allogeneic, in which bone marrow - derived stem
cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched with those of a patient.
If successful, this may lead to therapies for humans in which a patient's stem
cells will be reverted into iPSCs, then genetically repaired and
transplanted back into the bone marrow of the same patient.
His donated
cells — which were not touched by chemotherapy — were then
transplanted back into his body.
Once these
cells are put
back into the dogs with an IV catheter, the
transplant is complete.
The combination procedure is so intense that a bone marrow
transplant is done afterward, re-planting the healthy stem
cells back into the bone marrow.