Not exact matches
This is likely, as recently discovered
human globins appear to be involved
in cell signaling rather than oxygen
transport.
Unlike
humans, who use their lymphatic systems to produce and
transport white blood
cells, tuna use theirs to move two of their fins, researchers report today
in Science.
Their major hurdle: to come up with a replacement for hemoglobin (an iron - enriched protein
in red blood
cells that
transports oxygen from the lungs to the rest of the body) that can be directly introduced into the
human circulatory system.
The researchers have coated DNA nanostructures with virus capsid proteins
in order to significantly improve their
transport to
human cells; this could find uses for example
in enhanced drug delivery.
The study, «Facilitation of axon regeneration by enhancing mitochondrial
transport and rescuing energy deficits,» which has been published
in The Journal of
Cell Biology, suggests potential new strategies to stimulate the regrowth of
human neurons damaged by injury or disease.
Our technological expertise ranges from the most fundamental approaches to study membrane
transport in lymphocytes and dendritic
cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination,
human clinical studies
in cancer).
The aim of the present study was to evaluate glucose
transport and GS activity
in human satellite
cell cultures established from type 2 diabetic and control subjects.
Effect of preculturing
human satellite
cell cultures
in increasing concentrations of insulin on the basal and insulin - stimulated glucose
transport activity
in cultures of
human myofibers.
We describe here that
in cells derived from
human monocytes, i.e., macrophages and dendritic
cells, the B - subunit was internalized
in a receptor - dependent manner, but retrograde
transport to the biosynthetic / secretory pathway did not occur and part of the internalized protein was degraded
in lysosomes.
Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule
in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B -
cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for
transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC,
human induced pluripotent stem
cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R,
Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched
in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting
Creatine plays a central role
in the
transport and storage of energy
in every
human body
cell.
Some animal studies have shown that vanadium, like insulin, can promote amino acid
transport into the
cells, but various studies
in humans have not confirmed any increase of the muscle mass or athletic endurance after taking vanadium supplements [6].
, he effect of probiotic bacteria on transepithelial calcium
transport and calcium uptake
in human intestinal - like Caco - 2
cells, 2006
Sulfur enables the
transport of oxygen across
cell membranes and not only is oxygen needed for healthy cellular regeneration
in humans, it is the lack of oxygen that helps cancer
cells to grow.
Included
in this bundle: Biodiversity and
Human Interaction Biologists
Cell Division Cellular
Transport Chemistry of Life Ecology Evolution and Natural Selection Genetics
Human Body General Terms
Human Body Circulatory and Lymphatic Systems
Human Body Digestive System
Human Body Endocrine System
Human Body Excretory System
Human Body Integumentary System
Human Body Muscular System
Human Body Nervous System
Human Body Respiratory System
Human Body Skeletal System Photosynthesis and Cellular Respiration Plant Structure and Function Scientific Method Taxonomy The
Cell Types of Science What is Life
Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the
human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways
in which nutrients and water are
transported within animals, including
humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment
in different ways and that adaptation may lead to evolution Recognise that light appears to travel
in straight lines Use the idea that light travels
in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels
in straight lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of
cells used
in the circuit Compare and give reasons for variations
in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit
in a diagram
Covering: B1 -
Cell Structure and
transport B2 -
Cell Division B3 - Organisation and the Digestive System B4 - Organising animals and plants B5 - Communicable Diseases B6 - Preventing and Treating Disease B7 - Non-Communicable Diseases B8 - Photosynthesis B9 - Respiration B10 - The
Human Nervous System B11 - Hormonal Coordination B12 - Homeostasis
in Action (GCSE Biology Only) B13 - Reproduction B14 - Variation and Evolution B15 - Genetics and Evolution B16 - Adaptations, Interdependence and Competition B17 - Organising an Ecosystem B18 - Biodiversity and Ecosystems
The topics covered across the three years are: Biology
Humans as organisms - health, diet, exercise, nervous system, disease and control Living processes - respiration, reproduction,
transport in cells, Variation, evolution, inheritance & genetics - cloning, mutation and natural selection Ecosystems and habitats - food webs, interdependence and extinction