Sentences with phrase «transported into brain cells»

A cellular protein called PAK1 stimulates the growth of dendritic spines, or protrusions, that allow communication between neurons, and Roy had a hunch that this protein — when transported into brain cells — might help bring silent engrams back into direct awareness.

Not exact matches

As Pardridge studied the protein more carefully, he realized that it transports essential insulin into the cell and then out the other side, from which point the hormone travels into the brain to help regulate eating behavior.
The brain is protected by a barrier of cells that tightly regulates the transport of substances into this organ in order to prevent infection.
«Until now, it was not possible to look at how neurotransmitters are transported into cells across large regions of the brain,» says Aviad Hai, a postdoc in the Department of Biological Engineering and first author of a paper describing the technique in today's issue of Neuron.
One of the genes involved in feeding the big brain, called SLC2A1, builds a protein for transporting glucose from blood vessels into cells.
The endothelial cells have a receptor for transferrin that acts like a gatekeeper: When transferrin binds to a receptor on the blood side of the barrier, the endothelial cell transports it (and its iron cargo) to the other side and spits it out into the brain.
Genentech scientists led by Mark Dennis designed an antibody with two arms — one that binds to BACE1 and inhibits its activity and one that binds to the transferrin receptor and tricks endothelial cells into transporting the antibody across the blood - brain barrier.
Researchers at University of Florida Health have discovered the mechanics of how dopamine transports into and out of brain cells, a finding that could someday lead to more effective treatment of drug addictions and neurological disorders such as Parkinson's disease.
One theory suggests that because chromium helps cells be more sensitive to insulin, it also allows insulin to transport tryptophan — the precursor to serotonin — across the blood - brain barrier and into the central nervous system.
In addition, a functional BBB is manifested by a number of permanently active transport mechanisms, specifically expressed by brain capillary endothelial cells that ensure the transport of nutrients into the CNS and exclusion of blood - borne molecules that could be detrimental to the milieu required for neural transmission.
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