Sentences with phrase «transporter gene polymorphisms»

Relationship of serotonin transporter gene polymorphisms and haplotypes to mRNA transcription

A meta - analysis of the association between the serotonin transporter gene polymorphism (5 - HTTLPR) and trait anxiety

An exploratory genetic analysis: Associations between parent depression symptoms, child temperament, and the serotonin transporter gene polymorphism (5HTTLPR).

Not exact matches

Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.

A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4) has been associated with several dimensions of neuroticism and psychopathology, especially anxiety traits, but the predictive value of this genotype against these complex behaviors has been inconsistent.

Comparative analysis of length polymorphisms in the promoter region of the serotonin transporter gene (SLC6A4) in Cercopithecidae [abstract].

The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5 - HT2A and serotonin transporter linked polymorphic region -5-HTTLPR - of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E... (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.

The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5 - HT2A and serotonin transporter linked polymorphic region -5-HTTLPR - of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E

However, response to treatment may be predicted by baseline frontal lobe blood flow, and presence of polymorphisms of the 5 - hydroxytryptamine (5 - HT)-1 a gene, the LL genotype of the serotonin transporter linked polymorphic region (5 - HTTLPR) gene, and Val / Val homozygotes of the brain - derived neurotrophic factor (BDNF) gene.

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

In this study, measures of the quality and availability of social supports were found to moderate risk for depression associated with a history of maltreatment and the presence of the short (s) allele of the serotonin transporter gene promoter polymorphism (5 - HTTLPR).

We studied the well known functional polymorphism in the 5 ′ flanking regulatory (promoter) region of the gene (SLC6A4) coding for the serotonin transporter protein.

However, researchers at the University of California — Berkeley wanted to find out if there might a genetic component that could predict how couple interactions affect marital satisfaction.5 Specifically, the team decided to look at the 5 - HTTLPR polymorphism in the promoter region of the serotonin transporter gene.

This investigation examined the extent to which polymorphisms of the serotonin transporter linked promoter region (5 - HTTLPR) and the dopamine receptor D4 (DRD4) genes differentially influenced the development of attachment security and disorganization in maltreated and nonmaltreated infants at age 13 months, and the extent to which the efficacy of preventive interventions to promote attachment security were influenced by genetic variation.

Association analysis of the catechol - o - methyltransferase (COMT), serotonin transporter (5 - HTT) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive - compulsive disorder

Behavioural genetics studies examining the association between polymorphisms of the serotonin transporter gene and affective disorders (Uher & McGuffin 2008) as well as the association between environmental interactions with the serotonin transporter gene and affective disorders (Munafo et al. 2009; Risch et al. 2009) within a given population often produce inconsistent results, suggesting a more complex path from gene to disease.

Obsessive - compulsive disorder and the promoter region polymorphism (5 - HTTLPR) in the serotonin transporter gene (SLC6A4): a negative association study in the Afrikaner population

Serotonin transporter gene regulatory region polymorphism and anxiety - related traits in the Japanese

In relation to the association of infant attachment with a promoter polymorphism of the serotonin transporter gene, we have mentioned that gene expression may be affected by variation in the DNA sequence of the regulatory region of the gene.

Association between Dopamine Transporter Gene (DAT1) Polymorphisms and Eating Disorders with Binge Eating Behavior

Here, we examined the association between cultural values of individualism — collectivism and allelic frequency of the serotonin transporter functional polymorphism (5 - HTTLPR) as well as the role this culture — gene association may play in explaining global variability in prevalence of pathogens and affective disorders.

Adults who had been categorized as behaviorally inhibited at the age of 2 years exhibited a higher amygdala activation in response to unknown vs familiar faces16 compared with adults who were uninhibited as children, consistent with the notion that novel or ambiguous environmental stimuli of potential biological relevance activate the amygdala.17 Turning to genes that can influence the neurobiological bases of the processing of emotions, 2 common alleles, the short (S) and the long (L), in a variable repeat sequence of the serotonin transporter (5 - HTT) promoter polymorphism (5 - HTTLPR) on human chromosome 17q11 have been differently associated with greater amygdala activity in response to angry or fearful faces18 in healthy adults.

SEROTONIN TRANSPORTER LENGTH POLYMORPHISM, CHILDHOOD MALTREATMENT, AND CHRONIC DEPRESSION: A SPECIFIC GENE - ENVIRONMENT INTERACTION.

Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders

A meta - analysis of association studies between the 10 - repeat allele of a VNTR polymorphism in the 3 ′ UTR of dopamine transporter gene and attention deficit hyperactivity disorder

Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.

The effects of child maltreatment and polymorphisms of the serotonin transporter and dopamine D4 receptor genes and infant attachment and intervention efficacy

The human serotonin transporter gene linked polymorphism (5 - HTTLPR) shows ten novel allelic variants

Polymorphism in serotonin transporter gene associated with susceptibility to major depression

The present study examined gene — environment correlations and Gene × Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavgene — environment correlations and Gene × Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavGene × Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavgene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavgene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavgene in relation to symptoms of anxiety, depression, and oppositional behavior.